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Effect of Co-morbidities on the Development of Oral Feeding Ability in Pre-term Infants

Effect of Co-morbidities on the Development of Oral Feeding Ability in Pre-term Infants: a Prospective Study at Neonatology Unit of Assiut University Children Hospital

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04812249
Enrollment
160
Registered
2021-03-23
Start date
2021-05-01
Completion date
2021-12-31
Last updated
2021-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Feeding; Difficult, Newborn, Pre-Term

Brief summary

The aim of this study is to investigate the effect of co-morbidities on the timing of the achievement of full oral feeding in a cohort of pre-term infants and to evaluate their mode of feeding and feeding status at the time of hospital discharge.

Detailed description

It is widely acknowledged that pre-term infants frequently experience difficulties in attaining independent oral feeding, thus delaying the achievement of an adequate nutritional status and hospital discharge which - according to the American Academy of Pediatrics- requires the ability to feed exclusively by mouth(1-2) The development of oral feeding ability in pre-term infants is therefore a primary concern for neonatologists. Because of the immaturity of their body functions and the occurrence of co-morbidities, pre-term infants generally require a period of enteral feeding before they acquire the coordinated sucking ability that allows sufficient milk intake for growth(3) Furthermore, infant sucking skills differ between bottle- and breastfeeding (4), and pre-term infants have been reported to show a weaker and less coordinated suck (5). Few studies have investigated the timing and effect of co-morbidities on the achievement of independent oral skills. Jadcherla et al. (6) reported that infants born with a gestational age of \< 28 weeks showed a significant delay in attaining the transition to oral feeding, but it has also been found that the occurrence of morbidities negatively correlates with postmenstrual age at the time of achieving oral feeding skills (6),(7-8).

Interventions

OTHERClinical assessment

Clinical assessment and follow up of oral feeding ability

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 1 Days
Healthy volunteers
No

Inclusion criteria

1. A randomised sample of all newborns whose gestational age of \< 37 weeks . 2. infants who will be admitted to the NICU of Assiut University Children Hospital between 1 May and 31 October 2021.

Exclusion criteria

1. known congenital and/or chromosomal diseases. 2. death during hospitalisation, or transfer to another institution.

Design outcomes

Primary

MeasureTime frameDescription
The mean post-menstrual age in weeks at the time of starting and achieving full oral feeding will be evaluatedBaselineStatistical analysis will be made using SPSS version 12 software to assess the outcomes

Contacts

Primary ContactMohammed Khalaf Ali
mohamed.khalaf119911@gmail.com+201002424743
Backup ContactAmira Shalaby
shalaby406.as@gmail.com+201223958949

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026