Aging, Hiv, Incentives
Conditions
Keywords
hiv, aging, incentives
Brief summary
The objective of this study is to investigate the impact of incentives on clinical trial participation. 1) characterize key stakeholders' views on and assessment of incentives, 2) reach consensus among stakeholders on the factors to be considered when choosing incentives and their relative importance, 3) pilot test using vignettes for incentive decision making. We hypothesize that potential study participants make trade-offs regarding the characteristics of a research study when deciding whether to volunteer. This amendment is to document IRB reliance between UCR and USF.
Interventions
While this is not an intervention, there will be separate participants for the survey study and for the other components of the study (focus groups, interviews, conjoint analysis, piloting the vignettes
Sponsors
University of South Florida
University of California, Riverside
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* people living with HIV * biomedical HIV researchers * IRB members/bioethicists involved in HIV research
Exclusion criteria
* people under 18 years of age * people living outside of the United States * people who do not speak English
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| characterize how people living with HIV assess incentives | 3 months | we will conduct a 20 question quantitative survey of a nationally representative sample of people living with HIV asking about specific study payment information and scenarios |
| characterize key stakeholders' views on and assessment of incentives | 3 months | focus groups, and key informant interviews will be used to characterize key stakeholders' (people aging with HIV, IRB members, researchers) views on and assessment of incentives, with qualitative analysis of text done using RaDAR. We will use Conjoint Analysis (CJA) to estimate the relative importance (also called weight) that participants place on each study characteristic when choosing between different hypothetical studies. |
| pilot testing vignettes for incentive decision making | 3 months | We will develop HIV related vignettes (hypothetical scenarios) utilizing the data from outcomes 1 and 2. Specifically, once we have 6 to 8 study characteristics from Aim 2, and the final number of choices (2 - 3) per characteristic, we will use a factorial design to create 25 vignettes (hypothetical scenarios). Individuals from each group (i.e., study participants, researchers, and IRB members) will select the most appropriate incentive from a list of possibilities based on various scenarios. These vignettes will be based on studies identified in the literature and a review of consent forms and created in conjunction with the external advisory board (including pre-testing and revision prior to finalization). |
Countries
United States
Outcome results
None listed