Chronic Kidney Diseases
Conditions
Keywords
Chronic Kidney Disease patient on dialysis (stage 5D), Extracorporeal purification, Isonatremic dialysis, Sodium
Brief summary
Aim of this study is to evaluate, in a population of chronic kidney disease patients on dialysis (Stage 5D), the effect of treatment with isonatremic dialysis (vs conventional dialysis), during an observational period of 2 months each, on: * control of interdialytic weight gain * perdialytic tolerance in terms of adverse events occurring during all of the sessions of the study * body composition and thirst measured monthly during the 4 months of follow-up. * tolerance to treatment.
Interventions
PROCEDUREConventional dialysis treatment
Conventional dialysis treatment
PROCEDUREIsonatremic dialysis treatment
Isonatremic dialysis treatment
Sponsors
University Hospital, Montpellier
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Chronic Kidney Disease patient on dialysis (stage 5D) * With plasma sodium concentration between 130 and 140 mmol/L * Anuric * Patient dialysed with dialysis machine allowing isonatremic dialysis treatment
Exclusion criteria
* Patient with plasma sodium concentration below 130 or above 140 mmol/ * Pacemaker
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of interdialytic weight gain during treatment | 1, 2, 3 and 4 months after inclusion | change of interdialytic weight gain during treatment with isonatremic dialysis vs conventional dialysis during an observational period of 2 months each one. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Perdialytic tolerance in terms of adverse events occurring | 1, 2, 3 and 4 months after inclusion | Perdialytic tolerance in terms of adverse events occurring during all sessions of the study with isonatremic dialysis vs conventional dialysis for an observational period of 2 months each one. |
| Body composition | 1, 2, 3 and 4 months after inclusion | Body composition monthly during treatment with isonatremic dialysis vs conventional dialysis during an observational period of 2 months each one. |
| Rate of Tolerance | 1, 2, 3 and 4 months after inclusion | Rate of Tolerance during treatment with isonatremic dialysis vs conventional dialysis during an observational period of 2 months each one. |
Countries
France
Contacts
Primary ContactJean-Paul CRISTOL, Prof
Outcome results
None listed