COVID-19 and Acute Invasive Fungal Rhinosinusitis

The Impact of COVID-19 Outbreak on The Incidence of Acute Invasive Fungal Rhinosinusitis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04809480

Enrollment

Registered

2021-03-22

Start date

2017-01-01

Completion date

2020-12-31

Last updated

2021-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19

Keywords

fungal sinusitis, rhinosinusitis

Brief summary

Data for acute invasive rhinosinusitis was obtained from the Otorhinolaryngology departments at our tertiary hospital at the period from January 2017 to December 2020. Then the risk factors of comorbid diseases and fungal types between post-Covid-19 and non-Covid-19 groups regarding the incidence of invasive rhinosinusitis are compared.

Interventions

DIAGNOSTIC_TESTFungal rhinosinusitis

Pathology examination

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

15 Years to 90 Years

Inclusion criteria

* Patients of any age and sex. invasive rhinosinusoitis diagnosis based on clinical , endoscopic diagnosis * Positive findings for acute sinusitis on sinus computed tomography (CT) scan in addition to fungal determination by histopathological examination of specimen of affected tissues for detection of the type of fungi. * Positive PCR was confirmed from the patient's files at the isolation hospitals for COVID 19 group.

Exclusion criteria

* Patients who completed management outside our hospital

Design outcomes

Primary

Measure	Time frame	Description
Fungus detection	2 weeks	Culture and microscopic examination by the light microscope to examine the different types of the fungi using hematoxylin & eosin stain and Periodic acid-Schiff stain which is positive in fungi

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026