Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension, Pulmonary Hypertension, Pulmonary Hypertension Due to Left Heart Disease, Pulmonary Hypertension Due to Lung Diseases and Hypoxia, Pulmonary Hypertension, Primary, Pulmonary Hypertension, Primary, 2, Pulmonary Hypertension, Primary, 3, Pulmonary Hypertension, Primary, 4
Conditions
Brief summary
Establish a pulmonary hypertension registry and biorepository to lead towards a further understanding of the disease.
Detailed description
The aim of this project will be to establish a broad and wide-ranging registry and biorepository of blood samples from patients with pulmonary hypertension, including all WHO groups I-V to be used for future research in these areas. This will be both a retrospective and prospective project. The registry and biorepository will be utilized to study and grow our knowledge of the cellular mechanisms and mediators of the disease and, in turn, contribute to advancements in treatment.
Interventions
None listed
Sponsors
University of Kansas Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
1. The participant is a patient at TUKHS or has agreed to participate in a study approved by the KUMC Human Research Protection Program (HRPP) 2. The participant has a diagnosis of pulmonary hypertension confirmed by right heart catheterization 3. Patient is ≥ 18 years of age or older
Exclusion criteria
1. Participant declines to participate (living patients only) 2. Participant is unable to provide informed consent (living patients only)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Collect Clinical Data | From Enrollment to 6 Months | Collect clinically obtained data from current and deceased patients with pulmonary hypertension to support research. |
| Establish a Biorepository | From Enrollment to 6 Months | Establish a collection of biospecimens from patients with pulmonary hypertension. |
| Biospecimens Collection | From Enrollment to 12 Months | Correlate biospecimens to longitudinally collected individual patient data. |
| Collaborate | From Enrollment to 24 Months | Provide biospecimens to researchers investigating pulmonary hypertension. Separate IRB approval will be needed for these studies. |
Countries
United States
Contacts
Primary ContactLuigi R Boccardi, Ed.D., MPH
Backup ContactKimberly Cygan, MBA, BSN, RN
Outcome results
None listed