Anesthesia
Conditions
Brief summary
To compare the effectiveness of nebulization versus airway nerve block technique to achieve upper airway anesthesia for diagnostic fiberoptic bronchoscopy under moderate sedation.
Detailed description
Randomization was done using computer generated tables of random numbers: Group A (nebulized lignocaine group) as a control group (n = 60) received 5 ml of 10% lignocaine by air driven jet nebulizer for 20 min . Group B (nerve block group) (n = 60) received bilateral superior laryngeal nerve block and trans-tracheal instillation of 4 ml of 2% lignocaine, along with viscous xylocaine gargles twice. Patient tolerance was assessed using the Global Tolerance Score, based on a visual analogue scale ( VAS).
Interventions
OTHERGroup A
Patient will receive 5 ml of 10% lignocaine by air driven jet nebulizer for 20 min
OTHERGroup B
Patients will receive bilateral superior laryngeal nerve block and transtracheal instillation of 4 ml of 2% lignocaine, along with viscous xylocaine gargles twice
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients planned for diagnostic fiberoptic procedures such as broncho-alveolar lavage, endobronchial or transbronchial biopsies, or brush cytology.
Exclusion criteria
* Patients less than 21yrs old and patients more than 70 yrs old. * Severe respiratory failure (pH \< 7.35, partial arterial oxygen pressure \<55 mmHg despite supplemental oxygen). * Upper airway surgery or radiation, allergy to lidocaine, Propofol or midazolam, or bleeding disorder. * Hemodynamic instable patient or patient decompensated heart failure. * Epileptic patients, severe neurological or psychiatric disorder. * Patients requiring cryo-biopsy or endobronchial ultrasound because these procedures are performed under deep sedation including fiberoptic intubation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Global Tolerance Score | First two hours in the postoperative period | The Tolerance Score, defined as the arithmetic mean of global tolerance visual analogue score (VAS)and the mean of scores for the 4 specific sensations, was calculated. |
Contacts
Primary ContactHeba F Abd El-Aziz Toulan, Lecturer
Backup ContactSamar M Abdel Twab Soliman, Lecturer
Outcome results
None listed