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Treatment Uptake Chatbot for Eating Disorders

Developing an Optimized Conversational Agent or Chatbot to Facilitate Mental Health Services Use in Individuals With Eating Disorders

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04806165
Enrollment
205
Registered
2021-03-19
Start date
2021-03-09
Completion date
2022-05-09
Last updated
2023-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eating Disorders

Brief summary

Eating disorders (EDs) are serious mental illnesses associated with high morbidity and mortality, clinical impairment, and comorbid psychopathology. Although evidence-based treatments for EDs have been established, the treatment gap is wide. Indeed, \<20% of individuals with EDs receive treatment. There is need for a novel solution not only to identify individuals with EDs but also to encourage mental health services use and to address treatment barriers. This study aims to implement a conversational agent or chatbot that is optimized to increase mental health services use among individuals with EDs through such features as: 1) education on the seriousness and consequences of EDs; 2) engaging the user in motivational interviewing to overcome barriers to care; 3) providing a personalized recommendation for seeking intervention; 4) repeated check-ins with the user to encourage follow-up with care. This study will utilize a randomized optimization trial with adults who have completed screening on the National Eating Disorders Association (NEDA) website and screen positive for an ED but are not in treatment to determine chatbot feasibility and to generate data on the effect of the chatbot on motivation for treatment and mental health services use. This trial will employ the Multiphase Optimization Strategy framework, using a 2\^4 full factorial design, to randomly assign participants to a combination of the four proposed intervention components (n=16 conditions) to isolate the active ingredients.

Interventions

BEHAVIORALRepeated Administration

A discussion with the chatbot, including follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.

BEHAVIORALPersonalized Recommendation

A discussion with the chatbot, including identifying a personalized recommendation for accessing help for their eating disorder.

BEHAVIORALMotivational Interviewing

A discussion with the chatbot, including motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder.

BEHAVIORALCore Modules Only

A discussion with the chatbot, including only the core modules.

BEHAVIORALMotivational Interviewing, Personalized Recommendation, Repeated Administration

A discussion with the chatbot, including motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder, identifying a personalized recommendation for accessing help for their eating disorder, and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.

BEHAVIORALMotivational Interviewing, Repeated Administration

A discussion with the chatbot, including motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.

BEHAVIORALPersonalized Recommendation, Repeated Administration

A discussion with the chatbot, including identifying a personalized recommendation for accessing help for their eating disorder and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.

BEHAVIORALMotivational Interviewing, Personalized Recommendation

A discussion with the chatbot, including motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder and identifying a personalized recommendation for accessing help for their eating disorder.

BEHAVIORALPsychoeducation

A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders.

BEHAVIORALPsychoeducation, Repeated Administration

A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.

BEHAVIORALPsychoeducation, Personalized Recommendation

A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders and identifying a personalized recommendation for accessing help for their eating disorder.

BEHAVIORALPsychoeducation, Motivational Interviewing

A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders and motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder.

BEHAVIORALPsychoeducation, Motivational Interviewing, Personalized Recommendation

A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders, motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder, and identifying a personalized recommendation for accessing help for their eating disorder.

BEHAVIORALPsychoeducation, Personalized Recommendation, Repeated Administration

A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders, identifying a personalized recommendation for accessing help for their eating disorder, and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.

BEHAVIORALPsychoeducation, Motivational Interviewing, Repeated Administration

A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders, motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder, and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.

BEHAVIORALPsychoeducation, Motivational Interviewing, Personalized Recommendation, Repeated Administration

A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders, motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder, identifying a personalized recommendation for accessing help for their eating disorder, and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.

Sponsors

National Institute of Mental Health (NIMH)
CollaboratorNIH
Washington University School of Medicine
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* U.S. resident * English-speaking * Age 18 years or older * Owns a personal smartphone * Screens positive for a Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) clinical or subclinical eating disorder * Not currently receiving treatment for an eating disorder

Exclusion criteria

* Non-U.S. resident * Younger than 18 years old * Does not own a personal smartphone * Does not screen positive for a DSM-5 clinical or subclinical eating disorder * Screens positive for Avoidant Restrictive Food Intake Disorder * Currently receiving treatment for an eating disorder

Design outcomes

Primary

MeasureTime frameDescription
Rates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening2, 6, 14 Weeks from Engagement with the InterventionTreatment utilization was measured at each follow-up time point (2, 6, and 14 weeks), which was assessed via the prompt, Have you tried or used any type of mental health help (e.g., self-help app, telehealth/in-person counseling, etc.) for your concerns related to your eating, shape, or weight in the past \[2, 6, or 14\] weeks?. We defined a participant as having utilized treatment at the first time they responded, yes (vs. no) to this question. The data presented below indicate the rates of self-reported receipt of treatment/services utilization among participants assigned (component on) or not assigned (component off) to each of the four chatbot components (motivational interviewing, psychoeducation, personalized recommendations, repeated administration), as delineated by each time point during which the aforementioned item was assesed.

Secondary

MeasureTime frameDescription
Mean Willingness to Seek PsychotherapyBaseline, 2 Weeks, 6 Weeks, 14 WeeksParticipants' willingness to seek psychotherapy was assessed via an identical item in the baseline assessment (i.e., before the initial chatbot assessment) as well as each off the follow-up assessments delivered at 2, 6, and 14 weeks post-intervention. The item prompted users to rate their willingness to seek in-person or telehealth psychotherapy in subsequent weeks. Responses were rated on a Likert scale from 1 (not at all important/ready) to 7 (very important/ready). Mean values reported below indicate the average Likert scale willingness rating among all participants at each time point who did (component turned on) and did not (component turned off). Statistical analyses outline the time and component effects on changes in mean willingness to seek pyschotherapy from baseline to 14 weeks post-interventioon.
Mean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningBaseline, 2 weeks, 6 weeks, 14 weeksParticipants' attitudes toward making changes (i.e., motivation toward seeking help) to address their personal eating, shape, and weight concerns were measured via identical items in the baseline assessment, and in each of the 2, 6, and 14 week follow-up assessments. Items included, How important is it for you to change your eating, shape, or weight concerns? and, How ready are you to make changes in your eating, shape, or weight concerns?. Both items were rated on a Likert scale from 1 (not at all important/ready) to 7 (very important/ready), and the sum of the two questions was used as an index of change/motivation attitudes. Values below indicate the average Likert scale attitude rating (from 2 (lowest) to 14 (highest)) among all participants at each time point who did (component turned on) and did not (component turned off) receive each component. Analyses outline the time, component, and time by component interaction effects on changes in motivation attitudes since baseline.

Countries

United States

Participant flow

Recruitment details

Individuals who completed the NEDA screen and met all eligibility criteria were shown the baseline assessment. Individuals who completed the baseline, were U.S. residents, and endorsed owning a smartphone were shown the consent form. N= 205 individuals provided consent and were randomized to a condition.

Participants by arm

ArmCount
Repeated Administration
Repeated Administration: A discussion with the chatbot, including follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.
13
Personalized Recommendation
Personalized Recommendation: A discussion with the chatbot, including identifying a personalized recommendation for accessing help for their eating disorder.
12
Motivational Interviewing
Motivational Interviewing: A discussion with the chatbot, including motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder.
11
Core Modules Only
Core Modules Only: A discussion with the chatbot, including only the core modules.
14
Motivational Interviewing, Personalized Recommendation, Repeated Administration
Motivational Interviewing, Personalized Recommendation, Repeated Administration: A discussion with the chatbot, including motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder, identifying a personalized recommendation for accessing help for their eating disorder, and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.
13
Motivational Interviewing, Repeated Administration
Motivational Interviewing, Repeated Administration: A discussion with the chatbot, including motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.
13
Motivational Interviewing, Personalized Recommendation
Motivational Interviewing, Personalized Recommendation: A discussion with the chatbot, including motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder and identifying a personalized recommendation for accessing help for their eating disorder.
14
Personalized Recommendation, Repeated Administration
Personalized Recommendation, Repeated Administration: A discussion with the chatbot, including identifying a personalized recommendation for accessing help for their eating disorder and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.
13
Psychoeducation
Psychoeducation: A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders.
13
Psychoeducation, Repeated Administration
Psychoeducation, Repeated Administration: A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.
12
Psychoeducation, Personalized Recommendation
Psychoeducation, Personalized Recommendation: A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders and identifying a personalized recommendation for accessing help for their eating disorder.
13
Psychoeducation, Motivational Interviewing
Psychoeducation, Motivational Interviewing: A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders and motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder.
13
Psychoeducation, Motivational Interviewing, Personalized Recommendation
Psychoeducation, Motivational Interviewing, Personalized Recommendation: A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders, motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder, and identifying a personalized recommendation for accessing help for their eating disorder.
13
Psychoeducation, Personalized Recommendation, Repeated Administration
Psychoeducation, Personalized Recommendation, Repeated Administration: A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders, identifying a personalized recommendation for accessing help for their eating disorder, and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.
13
Psychoeducation, Motivational Interviewing, Repeated Administration
Psychoeducation, Motivational Interviewing, Repeated Administration: A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders, motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder, and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.
12
Psychoeducation, Motivational Interviewing, Personalized Recommendation, Repeated Administration
Psychoeducation, Motivational Interviewing, Personalized Recommendation, Repeated Administration: A discussion with the chatbot, including psychoeducational content to increase knowledge related to eating disorders, motivational interviewing techniques to help overcome barriers to seeking care for their eating disorder, identifying a personalized recommendation for accessing help for their eating disorder, and follow ups over the course of 2 weeks to encourage help seeking for their eating disorder.
13
Total205

Baseline characteristics

CharacteristicPersonalized RecommendationMotivational InterviewingCore Modules OnlyMotivational Interviewing, Personalized Recommendation, Repeated AdministrationMotivational Interviewing, Repeated AdministrationMotivational Interviewing, Personalized RecommendationPersonalized Recommendation, Repeated AdministrationPsychoeducationRepeated AdministrationPsychoeducation, Repeated AdministrationPsychoeducation, Personalized RecommendationPsychoeducation, Motivational InterviewingPsychoeducation, Motivational Interviewing, Personalized RecommendationPsychoeducation, Personalized Recommendation, Repeated AdministrationPsychoeducation, Motivational Interviewing, Repeated AdministrationPsychoeducation, Motivational Interviewing, Personalized Recommendation, Repeated AdministrationTotal
Age, Continuous29.50 years
STANDARD_DEVIATION 8.19
36.27 years
STANDARD_DEVIATION 13.98
38.42 years
STANDARD_DEVIATION 15.32
30.69 years
STANDARD_DEVIATION 10.93
37.69 years
STANDARD_DEVIATION 14.85
29.57 years
STANDARD_DEVIATION 7.74
29.57 years
STANDARD_DEVIATION 7.74
40.46 years
STANDARD_DEVIATION 18.33
28.31 years
STANDARD_DEVIATION 7.71
29.15 years
STANDARD_DEVIATION 9.51
32.42 years
STANDARD_DEVIATION 13.34
39.31 years
STANDARD_DEVIATION 14.06
31.10 years
STANDARD_DEVIATION 10.65
30.38 years
STANDARD_DEVIATION 12.47
32.38 years
STANDARD_DEVIATION 13.12
34.58 years
STANDARD_DEVIATION 14.09
30.00 years
STANDARD_DEVIATION 9.41
Age, Customized
18-24
2 participants2 participants3 participants5 participants3 participants3 participants4 participants5 participants6 participants3 participants2 participants4 participants6 participants4 participants4 participants5 participants61 participants
Age, Customized
25-34
7 participants4 participants4 participants4 participants3 participants9 participants2 participants5 participants5 participants4 participants3 participants5 participants3 participants5 participants3 participants5 participants71 participants
Age, Customized
35-44
3 participants2 participants1 participants2 participants2 participants1 participants1 participants2 participants1 participants3 participants4 participants1 participants1 participants2 participants3 participants2 participants31 participants
Age, Customized
45-54
0 participants2 participants3 participants2 participants4 participants1 participants3 participants1 participants1 participants0 participants2 participants3 participants3 participants1 participants1 participants0 participants27 participants
Age, Customized
55-64
0 participants1 participants3 participants0 participants1 participants0 participants2 participants0 participants0 participants1 participants1 participants0 participants0 participants1 participants0 participants1 participants11 participants
Age, Customized
65-74
0 participants0 participants0 participants0 participants0 participants0 participants1 participants0 participants0 participants1 participants1 participants0 participants0 participants0 participants1 participants0 participants4 participants
Ethnicity (NIH/OMB)
Hispanic or Latino
1 Participants1 Participants0 Participants1 Participants3 Participants1 Participants1 Participants1 Participants1 Participants0 Participants0 Participants2 Participants2 Participants1 Participants1 Participants1 Participants17 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
11 Participants10 Participants14 Participants12 Participants10 Participants13 Participants12 Participants12 Participants12 Participants12 Participants13 Participants11 Participants11 Participants12 Participants11 Participants12 Participants188 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
Asian
2 Participants0 Participants0 Participants0 Participants1 Participants1 Participants1 Participants1 Participants0 Participants0 Participants2 Participants1 Participants3 Participants0 Participants0 Participants2 Participants14 Participants
Race (NIH/OMB)
Black or African American
0 Participants0 Participants1 Participants1 Participants0 Participants1 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants3 Participants
Race (NIH/OMB)
More than one race
1 Participants1 Participants0 Participants0 Participants1 Participants1 Participants3 Participants0 Participants1 Participants0 Participants0 Participants3 Participants1 Participants1 Participants1 Participants2 Participants16 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants1 Participants1 Participants1 Participants2 Participants0 Participants0 Participants0 Participants1 Participants0 Participants0 Participants0 Participants0 Participants1 Participants1 Participants1 Participants9 Participants
Race (NIH/OMB)
White
9 Participants9 Participants12 Participants11 Participants9 Participants11 Participants9 Participants12 Participants11 Participants12 Participants11 Participants9 Participants9 Participants11 Participants10 Participants8 Participants163 Participants
Region of Enrollment
United States
12 participants11 participants14 participants13 participants13 participants14 participants13 participants13 participants13 participants12 participants13 participants13 participants13 participants13 participants12 participants13 participants205 participants
Sex: Female, Male
Female
10 Participants10 Participants14 Participants12 Participants13 Participants14 Participants13 Participants12 Participants9 Participants11 Participants13 Participants13 Participants13 Participants11 Participants11 Participants13 Participants192 Participants
Sex: Female, Male
Male
2 Participants1 Participants0 Participants1 Participants0 Participants0 Participants0 Participants1 Participants4 Participants1 Participants0 Participants0 Participants0 Participants2 Participants1 Participants0 Participants13 Participants
Sex/Gender, Customized
Female
10 Participants10 Participants14 Participants11 Participants12 Participants13 Participants13 Participants11 Participants9 Participants11 Participants13 Participants11 Participants13 Participants10 Participants10 Participants13 Participants184 Participants
Sex/Gender, Customized
Male
2 Participants1 Participants0 Participants1 Participants0 Participants0 Participants0 Participants1 Participants3 Participants1 Participants0 Participants0 Participants0 Participants2 Participants1 Participants0 Participants12 Participants
Sex/Gender, Customized
Non-binary/third gender
0 Participants0 Participants0 Participants1 Participants1 Participants0 Participants0 Participants1 Participants1 Participants0 Participants0 Participants1 Participants0 Participants1 Participants1 Participants0 Participants7 Participants
Sex/Gender, Customized
Prefer not to say
0 Participants0 Participants0 Participants0 Participants0 Participants1 Participants0 Participants0 Participants0 Participants0 Participants0 Participants1 Participants0 Participants0 Participants0 Participants0 Participants2 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
EG002
affected / at risk
EG003
affected / at risk
EG004
affected / at risk
EG005
affected / at risk
EG006
affected / at risk
EG007
affected / at risk
EG008
affected / at risk
EG009
affected / at risk
EG010
affected / at risk
EG011
affected / at risk
EG012
affected / at risk
EG013
affected / at risk
EG014
affected / at risk
EG015
affected / at risk
deaths
Total, all-cause mortality
0 / 130 / 120 / 110 / 140 / 130 / 130 / 140 / 130 / 130 / 120 / 130 / 130 / 130 / 130 / 120 / 13
other
Total, other adverse events
0 / 130 / 120 / 110 / 140 / 130 / 130 / 140 / 130 / 130 / 120 / 130 / 130 / 130 / 130 / 120 / 13
serious
Total, serious adverse events
0 / 130 / 120 / 110 / 140 / 130 / 130 / 140 / 130 / 130 / 120 / 130 / 130 / 130 / 130 / 120 / 13

Outcome results

Primary

Rates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening

Treatment utilization was measured at each follow-up time point (2, 6, and 14 weeks), which was assessed via the prompt, Have you tried or used any type of mental health help (e.g., self-help app, telehealth/in-person counseling, etc.) for your concerns related to your eating, shape, or weight in the past \[2, 6, or 14\] weeks?. We defined a participant as having utilized treatment at the first time they responded, yes (vs. no) to this question. The data presented below indicate the rates of self-reported receipt of treatment/services utilization among participants assigned (component on) or not assigned (component off) to each of the four chatbot components (motivational interviewing, psychoeducation, personalized recommendations, repeated administration), as delineated by each time point during which the aforementioned item was assesed.

Time frame: 2, 6, 14 Weeks from Engagement with the Intervention

Population: All participants who engaged with the intervention and completed the treatment utilization item at each follow up assessment (2, 6, and 14 weeks post intervention) are included. Participants in each of the 16 factorial conditions were sorted based on whether or not each of the four chatbot components were assigned. This method was used in order to understand which combination of components are essential in the design of an optimized chatbot for use in a future randomized controlled trial.

ArmMeasureGroupValue (COUNT_OF_PARTICIPANTS)
Motivational Interviewing OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 6 Weeks from Baseline5 Participants
Motivational Interviewing OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 14 Weeks from Baseline6 Participants
Motivational Interviewing OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 2 Weeks from Baseline40 Participants
Motivational Interviewing OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningCumulative Sum of Participants Reporting Treatment Receipt over Study Period51 Participants
Motivational Interviewing OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 2 Weeks from Baseline41 Participants
Motivational Interviewing OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 14 Weeks from Baseline9 Participants
Motivational Interviewing OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 6 Weeks from Baseline10 Participants
Motivational Interviewing OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningCumulative Sum of Participants Reporting Treatment Receipt over Study Period60 Participants
Personalized Recommendation OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningCumulative Sum of Participants Reporting Treatment Receipt over Study Period45 Participants
Personalized Recommendation OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 2 Weeks from Baseline45 Participants
Personalized Recommendation OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 6 Weeks from Baseline8 Participants
Personalized Recommendation OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 14 Weeks from Baseline6 Participants
Personalized Recommendation OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 14 Weeks from Baseline9 Participants
Personalized Recommendation OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 6 Weeks from Baseline7 Participants
Personalized Recommendation OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningCumulative Sum of Participants Reporting Treatment Receipt over Study Period36 Participants
Personalized Recommendation OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 2 Weeks from Baseline36 Participants
Psychoeducation OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 6 Weeks from Baseline3 Participants
Psychoeducation OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 14 Weeks from Baseline8 Participants
Psychoeducation OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 2 Weeks from Baseline42 Participants
Psychoeducation OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningCumulative Sum of Participants Reporting Treatment Receipt over Study Period42 Participants
Psychoeducation OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 2 Weeks from Baseline39 Participants
Psychoeducation OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 14 Weeks from Baseline7 Participants
Psychoeducation OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 6 Weeks from Baseline12 Participants
Psychoeducation OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningCumulative Sum of Participants Reporting Treatment Receipt over Study Period39 Participants
Repeated Administration OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningCumulative Sum of Participants Reporting Treatment Receipt over Study Period46 Participants
Repeated Administration OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 6 Weeks from Baseline5 Participants
Repeated Administration OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 2 Weeks from Baseline46 Participants
Repeated Administration OnRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 14 Weeks from Baseline8 Participants
Repeated Administration OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 2 Weeks from Baseline35 Participants
Repeated Administration OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 14 Weeks from Baseline7 Participants
Repeated Administration OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningCumulative Sum of Participants Reporting Treatment Receipt over Study Period35 Participants
Repeated Administration OffRates of Treatment/Services Utilization for Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningNumber of Participants Reporting New Treatment Receipt at 6 Weeks from Baseline10 Participants
Comparison: This analysis explores the effect of the motivational interviewing (MI) component on rates of treatment receipt over the entire study period. Results will help determine the proportional increase in odds of treatment seeking corresponding to receiving each chatbot component. Discrete time survival analysis was employed and models were fit with treatment seeking regressed on follow-up time (2-week, 6-week, or 14-week) and each chatbot component.p-value: 0.309Discrete Time Survival Analysis
Comparison: This analysis explores the effect of the personalized recommendation (PR) component on rates of treatment receipt over the entire study period. Results will help determine the proportional increase in odds of treatment seeking corresponding to receiving each chatbot component. Discrete time survival analysis was employed and models were fit with treatment seeking regressed on follow-up time (2-week, 6-week, or 14-week) and each chatbot component.p-value: 0.19Discrete Time Survival Analysis
Comparison: This analysis explores the effect of the psychoeducation (PE) component on rates of treatment receipt over the entire study period. Results will help determine the proportional increase in odds of treatment seeking corresponding to receiving each chatbot component. Discrete time survival analysis was employed and models were fit with treatment seeking regressed on follow-up time (2-week, 6-week, or 14-week) and each chatbot component.p-value: 0.69Discrete Time Survival Analysis
Comparison: This analysis explores the effect of the repeated administration (RA) component on rates of treatment receipt over the entire study period. Results will help determine the proportional increase in odds of treatment seeking corresponding to receiving each chatbot component. Discrete time survival analysis was employed and models were fit with treatment seeking regressed on follow-up time (2-week, 6-week, or 14-week) and each chatbot component.p-value: 0.038Discrete Time Survival Analysis
Comparison: This analysis provides results on the 2 week time point post Intervention and contributes to understanding of the effect of time since chatbot engagement on treatment receipt, regardless of the combination of the four chatbot components participants were assigned (ie., component turned off or on). Discrete time survival analysis was employed and models were fit with treatment seeking regressed on follow-up time (2-week, 6-week, or 14-week) and each chatbot component.p-value: 0.735Discrete Time Survival Analysis
Comparison: This analysis provides results on the 6 week time point post Intervention and contributes to understanding of the effect of time since chatbot engagement on treatment receipt, regardless of the combination of the four chatbot components participants were assigned (ie., component turned off or on). Discrete time survival analysis was employed and models were fit with treatment seeking regressed on follow-up time (2-week, 6-week, or 14-week) and each chatbot component.p-value: 0.001Discrete Time Survival Analysis
Comparison: This analysis provides results on the 14 week time point post Intervention and contributes to understanding of the effect of time since chatbot engagement on treatment receipt, regardless of the combination of the four chatbot components participants were assigned (ie., component turned off or on). Discrete time survival analysis was employed and models were fit with treatment seeking regressed on follow-up time (2-week, 6-week, or 14-week) and each chatbot component.p-value: 0.014Discrete Time Survival Analysis
Secondary

Mean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening

Participants' attitudes toward making changes (i.e., motivation toward seeking help) to address their personal eating, shape, and weight concerns were measured via identical items in the baseline assessment, and in each of the 2, 6, and 14 week follow-up assessments. Items included, How important is it for you to change your eating, shape, or weight concerns? and, How ready are you to make changes in your eating, shape, or weight concerns?. Both items were rated on a Likert scale from 1 (not at all important/ready) to 7 (very important/ready), and the sum of the two questions was used as an index of change/motivation attitudes. Values below indicate the average Likert scale attitude rating (from 2 (lowest) to 14 (highest)) among all participants at each time point who did (component turned on) and did not (component turned off) receive each component. Analyses outline the time, component, and time by component interaction effects on changes in motivation attitudes since baseline.

Time frame: Baseline, 2 weeks, 6 weeks, 14 weeks

Population: All participants randomized to the intervention (n=205) were included, with missing data accommodated using maximum likelihood estimation. This study uses a factorial design; participants were randomized to one of 16 conditions, with each condition receiving a different combination of the four chatbot components (motivational interviewing, psychoeducation, personalized recommendations, repeated administration) turned off or on. Data below are presented as such.

ArmMeasureGroupValue (MEAN)Dispersion
Motivational Interviewing OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningBaseline11.80 score on a scaleStandard Deviation 2.35
Motivational Interviewing OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening2 Weeks from Baseline10.73 score on a scaleStandard Deviation 2.59
Motivational Interviewing OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening6 Weeks from Baseline10.27 score on a scaleStandard Deviation 2.91
Motivational Interviewing OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening14 Weeks from Baseline9.87 score on a scaleStandard Deviation 3.09
Motivational Interviewing OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening14 Weeks from Baseline10.45 score on a scaleStandard Deviation 3.28
Motivational Interviewing OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening2 Weeks from Baseline10.70 score on a scaleStandard Deviation 2.95
Motivational Interviewing OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningBaseline11.05 score on a scaleStandard Deviation 2.89
Motivational Interviewing OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening6 Weeks from Baseline10.97 score on a scaleStandard Deviation 2.99
Personalized Recommendation OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningBaseline11.40 score on a scaleStandard Deviation 2.66
Personalized Recommendation OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening14 Weeks from Baseline10.45 score on a scaleStandard Deviation 3.27
Personalized Recommendation OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening2 Weeks from Baseline10.53 score on a scaleStandard Deviation 2.65
Personalized Recommendation OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening6 Weeks from Baseline10.62 score on a scaleStandard Deviation 3.01
Personalized Recommendation OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningBaseline11.45 score on a scaleStandard Deviation 2.68
Personalized Recommendation OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening2 Weeks from Baseline10.90 score on a scaleStandard Deviation 2.89
Personalized Recommendation OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening6 Weeks from Baseline10.64 score on a scaleStandard Deviation 2.93
Personalized Recommendation OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening14 Weeks from Baseline9.86 score on a scaleStandard Deviation 3.1
Psychoeducation OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening14 Weeks from Baseline10.01 score on a scaleStandard Deviation 3.28
Psychoeducation OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening6 Weeks from Baseline10.37 score on a scaleStandard Deviation 3.09
Psychoeducation OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening2 Weeks from Baseline10.31 score on a scaleStandard Deviation 2.93
Psychoeducation OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningBaseline11.40 score on a scaleStandard Deviation 2.7
Psychoeducation OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening14 Weeks from Baseline10.32 score on a scaleStandard Deviation 3.12
Psychoeducation OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening6 Weeks from Baseline10.90 score on a scaleStandard Deviation 2.81
Psychoeducation OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening2 Weeks from Baseline11.10 score on a scaleStandard Deviation 2.57
Psychoeducation OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningBaseline11.45 score on a scaleStandard Deviation 2.63
Repeated Administration OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening14 Weeks from Baseline10.54 score on a scaleStandard Deviation 3.02
Repeated Administration OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningBaseline11.34 score on a scaleStandard Deviation 2.76
Repeated Administration OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening6 Weeks from Baseline10.89 score on a scaleStandard Deviation 2.72
Repeated Administration OnMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening2 Weeks from Baseline10.86 score on a scaleStandard Deviation 2.6
Repeated Administration OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening2 Weeks from Baseline10.57 score on a scaleStandard Deviation 2.94
Repeated Administration OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening6 Weeks from Baseline10.36 score on a scaleStandard Deviation 3.19
Repeated Administration OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder Screening14 Weeks from Baseline9.83 score on a scaleStandard Deviation 3.33
Repeated Administration OffMean Attitude Toward Change for Concerns Related to Eating, Shape, or Weight Concerns Among All Participants Randomized to the Intervention Following Online Eating Disorder ScreeningBaseline11.50 score on a scaleStandard Deviation 2.57
Comparison: This analysis explores the time effect of attitudinal changes over the 14 week course of the study, regardless of the combination of components participants were assigned (ie., component turned off or on). Results will help determine whether mean participant attitudes toward change for concerns related to their eating, weight, and/or shape concerns varied based on the time elapsed since engagement with the intervention (ie., do attitudinal changes post-inntervention endure over time?).p-value: <0.001Linear Mixed Effects Model
Comparison: Analyses were conducted to determine the interaction effects of time since intervention and each of the four chatbot components. This analysis explores the interaction effects of time and the motivational interviewing (MI) component on participant attitudes toward change for concerns related to their eating, weight, and/or shape concerns since engagement with the intervention.p-value: 0.026Linear Mixed Effects Model
Comparison: Analyses were conducted to determine the interaction effects of time since intervention and each of the four chatbot components. This analysis explores the interaction effects of time and the personalized recommendation (PR) component on participant attitudes toward change for concerns related to their eating, weight, and/or shape concerns since engagement with the intervention.p-value: 0.465Linear Mixed Effects Model
Comparison: Analyses were conducted to determine the interaction effects of time since intervention and each of the four chatbot components. This analysis explores the interaction effects of time and the psychoeducation (PE) component on participant attitudes toward change for concerns related to their eating, weight, and/or shape concerns since engagement with the intervention.p-value: 0.536Linear Mixed Effects Model
Comparison: Analyses were conducted to determine the interaction effects of time since intervention and each of the four chatbot components. This analysis explores the interaction effects of time and the repeated administration (RA) component on participant attitudes toward change for concerns related to their eating, weight, and/or shape concerns since engagement with the intervention.p-value: 0.049Linear Mixed Effects Model
Secondary

Mean Willingness to Seek Psychotherapy

Participants' willingness to seek psychotherapy was assessed via an identical item in the baseline assessment (i.e., before the initial chatbot assessment) as well as each off the follow-up assessments delivered at 2, 6, and 14 weeks post-intervention. The item prompted users to rate their willingness to seek in-person or telehealth psychotherapy in subsequent weeks. Responses were rated on a Likert scale from 1 (not at all important/ready) to 7 (very important/ready). Mean values reported below indicate the average Likert scale willingness rating among all participants at each time point who did (component turned on) and did not (component turned off). Statistical analyses outline the time and component effects on changes in mean willingness to seek pyschotherapy from baseline to 14 weeks post-interventioon.

Time frame: Baseline, 2 Weeks, 6 Weeks, 14 Weeks

Population: The analysis population included those individuals who did not report utilizing treatment/services at any of the three follow-up assessments. Treatment utilization was assessed via the item,Have you tried or used any type of mental health help (e.g., self-help app, telehealth/in-person counseling, etc.) for your concerns related to your eating, shape, or weight in the past past \[2, 6, or 14\] weeks? Participants who did not respond yes to this item were included in this analysis.

ArmMeasureGroupValue (MEAN)Dispersion
Motivational Interviewing OnMean Willingness to Seek Psychotherapy6 Weeks from Baseline3.77 score on a scaleStandard Deviation 2.07
Motivational Interviewing OnMean Willingness to Seek Psychotherapy14 Weeks from Baseline3.71 score on a scaleStandard Deviation 1.98
Motivational Interviewing OnMean Willingness to Seek Psychotherapy2 Weeks from Baseline3.88 score on a scaleStandard Deviation 2.03
Motivational Interviewing OnMean Willingness to Seek PsychotherapyBaseline4.64 score on a scaleStandard Deviation 1.92
Motivational Interviewing OffMean Willingness to Seek PsychotherapyBaseline4.23 score on a scaleStandard Deviation 2.03
Motivational Interviewing OffMean Willingness to Seek Psychotherapy6 Weeks from Baseline3.56 score on a scaleStandard Deviation 2.13
Motivational Interviewing OffMean Willingness to Seek Psychotherapy2 Weeks from Baseline3.47 score on a scaleStandard Deviation 1.9
Motivational Interviewing OffMean Willingness to Seek Psychotherapy14 Weeks from Baseline3.41 score on a scaleStandard Deviation 1.77
Personalized Recommendation OnMean Willingness to Seek Psychotherapy6 Weeks from Baseline4.00 score on a scaleStandard Deviation 2.1
Personalized Recommendation OnMean Willingness to Seek Psychotherapy2 Weeks from Baseline3.85 score on a scaleStandard Deviation 1.84
Personalized Recommendation OnMean Willingness to Seek Psychotherapy14 Weeks from Baseline3.11 score on a scaleStandard Deviation 1.78
Personalized Recommendation OnMean Willingness to Seek PsychotherapyBaseline4.30 score on a scaleStandard Deviation 1.88
Personalized Recommendation OffMean Willingness to Seek Psychotherapy2 Weeks from Baseline3.60 score on a scaleStandard Deviation 2.08
Personalized Recommendation OffMean Willingness to Seek PsychotherapyBaseline4.57 score on a scaleStandard Deviation 2.05
Personalized Recommendation OffMean Willingness to Seek Psychotherapy14 Weeks from Baseline4.00 score on a scaleStandard Deviation 1.89
Personalized Recommendation OffMean Willingness to Seek Psychotherapy6 Weeks from Baseline3.45 score on a scaleStandard Deviation 2.06
Psychoeducation OnMean Willingness to Seek Psychotherapy14 Weeks from Baseline3.62 score on a scaleStandard Deviation 2.11
Psychoeducation OnMean Willingness to Seek PsychotherapyBaseline4.30 score on a scaleStandard Deviation 2.08
Psychoeducation OnMean Willingness to Seek Psychotherapy2 Weeks from Baseline3.96 score on a scaleStandard Deviation 1.88
Psychoeducation OnMean Willingness to Seek Psychotherapy6 Weeks from Baseline3.86 score on a scaleStandard Deviation 2.19
Psychoeducation OffMean Willingness to Seek Psychotherapy6 Weeks from Baseline3.44 score on a scaleStandard Deviation 1.93
Psychoeducation OffMean Willingness to Seek PsychotherapyBaseline4.60 score on a scaleStandard Deviation 1.87
Psychoeducation OffMean Willingness to Seek Psychotherapy14 Weeks from Baseline3.53 score on a scaleStandard Deviation 1.59
Psychoeducation OffMean Willingness to Seek Psychotherapy2 Weeks from Baseline3.43 score on a scaleStandard Deviation 2.06
Repeated Administration OnMean Willingness to Seek Psychotherapy2 Weeks from Baseline4.71 score on a scaleStandard Deviation 1.79
Repeated Administration OnMean Willingness to Seek Psychotherapy6 Weeks from Baseline3.93 score on a scaleStandard Deviation 2.12
Repeated Administration OnMean Willingness to Seek PsychotherapyBaseline4.69 score on a scaleStandard Deviation 2.03
Repeated Administration OnMean Willingness to Seek Psychotherapy14 Weeks from Baseline3.85 score on a scaleStandard Deviation 1.72
Repeated Administration OffMean Willingness to Seek Psychotherapy14 Weeks from Baseline3.44 score on a scaleStandard Deviation 1.96
Repeated Administration OffMean Willingness to Seek PsychotherapyBaseline4.25 score on a scaleStandard Deviation 1.92
Repeated Administration OffMean Willingness to Seek Psychotherapy2 Weeks from Baseline3.11 score on a scaleStandard Deviation 1.83
Repeated Administration OffMean Willingness to Seek Psychotherapy6 Weeks from Baseline3.52 score on a scaleStandard Deviation 2.06
Comparison: Analyses were conducted to determine the effects of each of the four chatbot components on secondary outcomes. This analysis in particular explores the effects of the motivational interviewing component (MI) on participant willingness to seek psychotherapy for concerns their disordered weight and shape behaviors and thoughts since engagement with the intervention. Linear mixed effects models incorporated a random intercept to accommodate the correlation of repeated measures within participants.p-value: 0.25Linear Mixed Effects Model
Comparison: Analyses were conducted to determine the effects of each of the four chatbot components on willingness to seek psychotherapy. This analysis in particular explores the effects of the psychoeducation component (PE) on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns since engagement with the intervention.p-value: 0.44Linear Mixed Effects Model
Comparison: Analyses were conducted to determine the effects of each of the four chatbot components on willingness to seek psychotherapy. This analysis in particular explores the effects of the personalized recommendation component (PR) on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns since engagement with the intervention.p-value: 0.44Linear Mixed Effects Model
Comparison: Analyses were conducted to determine the effects of each of the four chatbot components on willingness to seek psychotherapy. This analysis in particular explores the effects of the repeated administration component (RA) on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns since engagement with the intervention.p-value: 0.53Linear Mixed Effects Model
Comparison: This analysis provides results on the 2 week time point post Intervention and contributes to understanding of the effect of time since chatbot engagement on willingness to seek psychotherapy, regardless of the combination of the four chatbot components participants were assigned (ie., component turned off or on).p-value: 0.07Linear Mixed Effects Model
Comparison: This analysis provides results on the 6 week time point post Intervention and contributes to understanding of the effect of time since chatbot engagement on willingness to seek psychotherapy, regardless of the combination of the four chatbot components participants were assigned (ie., component turned off or on).p-value: 0.01Linear Mixed Effects Model
Comparison: This analysis provides results on the 14 week time point post Intervention and contributes to understanding of the effect of time since chatbot engagement on willingness to seek psychotherapy, regardless of the combination of the four chatbot components participants were assigned (ie., component turned off or on).p-value: 0.042Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 2-week time since engagement with the intervention and the motivational interviewing (MI) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.89Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 6-week time since engagement with the intervention and the motivational interviewing (MI) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.69Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 14-week time since engagement with the intervention and the motivational interviewing (MI) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.4Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 2-week time since engagement with the intervention and the psychoeducation (PE) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.55Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 6-week time since engagement with the intervention and the psychoeducation (PE) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.32Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 14-week time since engagement with the intervention and the psychoeducation (PE) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.63Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 2-week time since engagement with the intervention and the personalized recommendation (PR) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.9Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 6-week time since engagement with the intervention and the personalized recommendation (PR) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.27Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 14-week time since engagement with the intervention and the personalized recommendation (PR) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.42Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 2-week time since engagement with the intervention and the repeated administration (RA) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.04Linear Mixed Effects Model
Comparison: This analysis explores the interaction effects of 6-week time since engagement with the intervention and the repeated administration (RA) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.16Multilevel Models
Comparison: This analysis explores the interaction effects of 14-week time since engagement with the intervention and the repeated administration (RA) component on participant willingness to seek psychotherapy for concerns related to their eating, weight, and/or shape concerns. since engagement with the intervention.p-value: 0.99Linear Mixed Effects Model

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026