Skin Condition
Conditions
Brief summary
60 subjects were recruited and divided into placebo group and fermented grape drinks group.
Detailed description
In this study, using a fermented grape drinks made of fermented grapes with fruit and vegetable powder to explore whether it can improve the skin's condition and achieve anti-inflammatory effects. Sixty subjects were recruited and divided into placebo group and fermented grape drinks group. After drinking for 8 weeks, skin test and blood biochemical analysis were performed.
Interventions
DIETARY_SUPPLEMENTplacebo group
subjects drank 50 ml , 1 bottle a day for 8 week
DIETARY_SUPPLEMENTfermented grape drinks
subjects drank 50 ml , 1 bottle a day for 8 week
Sponsors
TCI Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1. Dry skin. 2. Rough skin 3. Large pores 4. Dark yellow complexion 5. Sagging skin
Exclusion criteria
1. Skin disorders 2. Liver diseases 3. Kidney diseases 4. Allergy to cosmetics, drugs, or foods 5. Pregnant and lactating women 6. People who had any cosmetic procedures before 4 weeks of the study 7. Area of facial spot over 3 cm2 8. Vegan 9. People who took collagen supplements in the past 3 months.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| skin brightness | 8 week | The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using corneometer CM825 to examine skin brightness (The higher the value, the more water content, C.U., corneometer units ) |
| skin elasticity | 8 week | The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using cutometer dual MPA580 to examine skin elasticity (The closer the R2 value is to 1, the better the elasticity and no unit) |
| skin moisture | 8 week | The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using probe system GL2000 & MPA10 to examine skin moisture (The higher the value, the higher the gloss, no unit) |
| skin spot | 8 week | The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then usig VISIA-CR to examine skin spot (The higher the value, the larger the pore area, mm2) |
| skin wrinkle | 8 week | The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using VISIOSCAN-VC20 to examine skin wrinkle (The higher the value, the more wrinkles, surface evaluation of wrinkles, SEW) |
| inflammatory cytokines | 8 week | The subjects divided into a placebo group (n=30) and an experimental group (n=30). Each subject was informed to consume one bottle of a 50 mL of grape drink or a placebo drink daily for 8 weeks, then using ELISA kit to examine inflammatory cytokines (pg/ml) |
Countries
Taiwan
Outcome results
None listed