Scleroderma, Systemic
Conditions
Keywords
Trichoscopy, Dermoscopy, Systemic Scleroderma, Scalp
Brief summary
* Few data are available on scalp involvement in systemic scleroderma. * Few data are available on the association between scalp abnormalities and features of systemic scleroderma * Trichoscopy is a simple, reproducible, noninvasive examination that is part of the examination of hairy areas in routine dermatologic practice * There is a lack of simple, noninvasive examinations to evaluate patients with systemic scleroderma The objective will be to evaluate the contribution of trichoscopy in the evaluation of patients with systemic scleroderma
Interventions
PROCEDUREpicture
We will perform a non-invasive assessment of the scalp with a dermoscope by taking two standardized pictures on the frontal area and the occipital area in order to a blinded analysis of trichoscopic patterns
Sponsors
University Hospital, Lille
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient who fulfils the Systemic scleroderma ACR-EULAR 2013 criteria * Signed informed consent * Being social insured
Exclusion criteria
* Patients aged less than 18 years old * patients under legal protection * patients deprived of their liberty * patients in emergency situations * patients who refused or unable to give informed consent * For the control group: sclap inflammatory disease active the day of the examination
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of elementary lesions observed by trichoscopic assessment of the scalp | Baseline | Comparison of the frequencies of elementary lesions visualized in patients with systemic scleroderma and healthy subjects |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between visceral damage of systemic scleroderma and trichoscopic features | Baseline | Frequency of visceral damage of systemic scleroderma: pulmonary hypertension, lung fibrosis, kidney failure. |
| Correlation between global severity of systemic scleroderma and trichoscopic features | Baseline | Correlation between EUSTAR score, Rodnan score, Medsger's score and trichoscopic features |
| Correlation between autoimmune profile of sclerodermic patients and trichoscopic features | Baseline | Correlation of antibodies, inflammatory profile of patients with trichoscopic features. |
Countries
France
Contacts
CONTACTVincent Sobanski, MD
PRINCIPAL_INVESTIGATORVincent Sobanski, MD
University Hospital, Lille
Outcome results
None listed