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Virtual Reality Place in the Management of Body Dysmorphia Disorders in Anorexia Nervosa

Virtual Reality Place in the Management of Body Dysmorphia Disorders in Anorexia Nervosa : Comparison of the Recommended Management and Virtual Reality Care Programs With or Without Multisensory Remedy

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04804800
Acronym
PROSANOR
Enrollment
150
Registered
2021-03-18
Start date
2022-09-30
Completion date
2026-05-31
Last updated
2022-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia Nervosa, Dysmorphophobia

Keywords

Anorexia Nervosa, Dysmorphophobia, Body distortions, Multisensory remediation, Virtual Reality

Brief summary

Body distortions are responsible for anorexic behavior reinforcing loops. It is necessary to target this behavior and develop appropriate therapies taking into account the perceptual (implicit) and conceptual (explicit) phenomenon of body representations. The main originality of the proposed program consists on combining virtual visual impulses and multisensory recalibration (touch, proprioception, vestibular sensations) in order to compare the body distortions evolution in anorexic patients with or without a multimodal care program including Virtual Reality from its own body scan, coupled or not to a multisensory remediation.

Detailed description

Rapid weight loss associated with mental anorexia leads to dysmorphophobia and body distortions. Patients perceive themselves to be bigger than they really are. Body distortions are responsible for anorexic behavior reinforcing loops. It is then necessary to target this behavior and develop appropriate therapies taking into account the perceptual (implicit) and conceptual (explicit) phenomenon of body representations. The current treatment programs which are recommended by the Haute Autorité de Santé (HAS) in France focus on the somatic, nutritional, individual and family psychological aspects. These recommendations hardly mention the bodily distortion phenomenon which frequently leads patients to relapse into the disease. The 3D body scanner enables to get awareness of the body through visual feedback allowing the patient to get a reassuring overview of her weight development. This projects aims to combine virtual visual impulses and multisensory recalibration (touch, proprioception, vestibular sensations) in order to compare the body distortions evolution in anorexic patients with or without a multimodal care program including Virtual Reality from its own body scan coupled or not to a multisensory remediation.

Interventions

OTHERExperimental group 1 : Virtual Reality

Patients benefit from the care recommended by the HAS, the virtual reality program and time for relaxation and body scan.

OTHERExperimental group 2 : Virtual Reality + Multi Sensorial Remediation

Patients benefit from the care recommended by the HAS, the virtual reality program, the multisensory remediation, and also the body scan.

Sponsors

Lille Catholic University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE

Intervention model description

This study presents three groups of patients : * The control group : The patients benefit from the care recommended by the HAS, relaxation times and body scan. * The experimental group 1 : The patients benefit from the care recommended by the HAS, the virtual reality program and relaxation times and body scan. * The experimental group 2 : The patients benefit from the care recommended by the HAS, the virtual reality program, the multi-sensory remediation and relaxation times and body scan.

Eligibility

Sex/Gender
FEMALE
Age
15 Years to 26 Years
Healthy volunteers
No

Inclusion criteria

* Female * Age ≥ 15 to ≤ 26 years old * Anorexic nervosa eating disorder according to the criteria of Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM 5). As patients are hospitalized for anorexic nervosa, the medical diagnosis of each care center participating in the inclusions will be trusted * Patient hospitalized (full hospitalization or day hospital) in one of the investigative centers for a minimum period of 6 weeks * 14 ≤ BMI ≤ 18.5 for adult patients. For minors, Cole's curves will be used. The Body mass index (BM)I should be between the 1st percentile and the 10th percentile (if the weight curve shows a clear break indicating abnormal weight loss). For example, for a 15-year-old girl, the BMI should be between 14.5 and 16.8. * Presence of body distortion (BSC ≥ 20%) * French language mastery * Affiliation to a social security system * Signature of informed consent to participate in this study by the patient and by her parents in the case of underage patients

Exclusion criteria

* Associated major mental disorders (psychotic disorders, bipolar disorders, major depression) * Neurological disorders (pyramidal or extrapyramidal syndromes) * Substance addiction (drugs, alcohol) * Any disorder likely to impair the reasoning, discernment or judgment abilities * Psychological incapacity to answer the questionnaires * Medical contraindication to the practice of physical activity (identical contraindication to people without anorexia. In fact, appropriate physical activity is prescribed in anorexic patients in order to reduce the cardiovascular risks, osteopenia or anxiety and allow them to become aware of an adapted physical practice (reduction of anarchic physical hyperactivity) * Participation in other research programs or psychomotor treatments in parallel * Pregnant or breastfeeding woman * Persons under guardianship, curatorship or legal protection * Blindness, eye infections, mask wounds, poorly balanced epilepsy, psychiatric disorders incompatible with virtual reality

Design outcomes

Primary

MeasureTime frameDescription
Change in Body Dimensions Estimation task6 weeksBody overestimation bias will be assessed by the Body Dimensions Estimation task.

Secondary

MeasureTime frameDescription
Change in Physical self description questionnaire6 weeksThe Physical self description will be measured by the Physical Self Description Questionnaire (PSQD). This questionnaire estimates 11 sub-dimensions of the physical self from 70 items on a continuum ranging from 1 (very negative perception) to 6 (very positive perception).
Change in Body Image Questionnaire6 weeksPatients bodily satisfaction will be assessed by the Body Image Questionnaire. This questionnaire consists of 19 items scored on 5 points. It gives a total body satisfaction score between 19 and 95 and 4 scores relative to 4 different factors (accessibility/closure, satisfaction/dissatisfaction, active/passive, serenity/tension).
Change in Body Shape Questionnaire6 weeksThe womens body image concerns will be evaluated by the Body Shape Questionnaire. This 34-items questionnaire is scored from 1 (= never) to 6 (= always) to obtain a global score.
Change in Eating Disorder Examination Questionnaire6 weeksEating disorders will be assessed by the Eating Disorder Examination Questionnaire (EDE-Q). This questionnaire is divided into several sub-scores: restriction, dietary concerns, body shape concerns and weight concerns. It has 30 items scored from 0 (= no day) to 6 (= every day). A score for each subscale and an overall score can be obtained.
Anxiety measured by the State-Trait Anxiety Inventory (STAI-Etat-Trait)6 weeksAnxiety will be measured by the STAI-Etat-Trait . Each of the dimensions (STAI-state and Stai-trait) are measured by 20 items scored from 1 (= no or never) to 4 (= yes or almost always) which is summarized by a score.
Change in Weight gain6 weeksWeight gain will be measured by weighting.

Contacts

Primary ContactAmélie Lansiaux, PhD, MD
lansiaux.amelie@ghicl.net03.20.22.52.69
Backup ContactAnne-Sophie Blain, CRA
blain.anne-sophie@ghicl.net03.20.22.57.32

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026