Healthy
Conditions
Keywords
cycling, cognition, sage, memory, fatigue
Brief summary
Extracts of sage have been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has clearly demonstrated the possible effects in healthy individuals in fatiguing conditions. The current study investigates the effects of this supplementation in healthy males and females versus placebo on cognition, heart rate and perceived exertion, during a fatiguing cycling exercise.
Detailed description
Healthy males and females will be tested in fresh and fatiguing conditions to mimic individuals at the beginning or during a competition where cognitive function are important for decision making for example. Tests will be conducted during the warm-up (fresh), during fatiguing situations (during two consecutive 10-minutes pedaling exercises) and during recovery. Tests will include a reverse digit memory test (from 3 to 7 digits), a stroop test, a simple reaction time test. Moreover, heart rate and rating of perceived exertion will be quantified.
Interventions
DIETARY_SUPPLEMENTSage extracts Cognivia
Cognivia is composed of 400 mg of aqueous extract from Salvia officinalis and the remaining 200 mg contained 50 µL of Salvia lavandulaefolia essential oil and encapsulated with gum acacia. It will be administrated the the morning before the endurance test (oral administration).
DIETARY_SUPPLEMENTPlacebo
Made with maltodextrin. It will be administrated the the morning before the endurance test (oral administration).
Sponsors
University of Burgundy
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Body mass index lower than 27 and waist size lower than 94 cm * physical activity higher than 3 hours a week * written informed consent
Exclusion criteria
* more than 12 hours training a week * asthmatic, smokers or under medicinal drugs * dietary supplement, sports drink, special dietary food or functional food, of any kind, liable or presented as liable to enhance physical performances
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Memory | During the 10-minutes warm-up, immediately after the first 10-minutes fatiguing exercise, after the second 10-minutes fatiguing exercise and after a five minutes recovery period | Changes in percent number of correct answers during a reverse digit immediate memory test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate | At rest, at the end of the 10-minutes warm-up, at the end of the first 10-minutes fatiguing exercise, at the end of the second 10-minutes fatiguing exercise, after 5 minutes of recovery | Changes in heart rate using a polar belt (in beats per minutes) |
| Rating of perceived exertion | At rest, at the end of the 10-minutes warm-up, at the end of the first 10-minutes fatiguing exercise, at the end of the second 10-minutes fatiguing exercise, after 5 minutes of recovery | Changes in rating of perceived exertion using a visual analogic scale (1-10) |
| Reaction time | During the 10-minutes warm-up, immediately after the first 10-minutes fatiguing exercise, after the second 10-minutes fatiguing exercise and after a five minutes recovery period | Changes in reaction time between a visual signal and manual action |
| Stroop performance | During the 10-minutes warm-up, immediately after the first 10-minutes fatiguing exercise, after the second 10-minutes fatiguing exercise and after a five minutes recovery period | Changes in percent number of correct answers during a stroop test |
| Stroop reaction time | During the 10-minutes warm-up, immediately after the first 10-minutes fatiguing exercise, after the second 10-minutes fatiguing exercise and after a five minutes recovery period | Changes in reaction time during the stroop test |
Countries
France
Outcome results
None listed