Sepsis
Conditions
Keywords
Sepsis, clinical intuition, emergency department
Brief summary
Sepsis is a syndrome involving infection and an abnormal systemic inflammatory response in the infected organism, resulting in organ dysfunction and possibly death. It is a major cause of hospital mortality. A large proportion of sepsis diagnoses are made in emergency departments. Early diagnosis and appropriate treatment have been shown to reduce mortality from this disease. In a context of limited resources, it is therefore important to be able to quickly stratify patients presenting to the emergency department with a suspected infection into those who require rapid and intensive management because they are at risk of developing sepsis and septic shock and those who can be managed conventionally The objective of this study is to compare the clinical intuition of emergency room physicians and nurses with the qSOFA score to predict the clinical course of patients presenting to the emergency room with potential sepsis.
Interventions
None listed
Sponsors
Centre Hospitalier le Mans
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients presenting to one of the participating emergency departments with suspected infection, defined as the presence of at least one of these parameters: Temperature ≥ 38°C ou \< 36°C measured in the emergency room Chills (in the emergency room or on recent history) * No objection to participation in the study
Exclusion criteria
* Minor patient (\<18 years) * Patient under guardianship or other protective measure * Patient unable to understand research information * Patient refusing the use of their data for research purposes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Compare emergency physicians' clinical intuition versus qSOFA score for prediction of 30-day mortality in patients with suspected infection | 1 month after inclusion | We compare the area under the ROC curve of each test (Emergency physicians' clinical intuition versus qSOFA score) to predict 30-day mortality in patients with suspected infection |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Compare emergency physicians' clinical intuition versus qSOFA score for prediction of 72 hours mortality in patients with suspected infection | 72 hours after inclusion | We compare the area under the ROC curve of each test (Emergency physicians' clinical intuition versus qSOFA score) to predict 72 hours mortality in patients with suspected infection |
Countries
France
Contacts
Primary ContactChristelle JADEAU
Backup ContactAdrien PICAUD
Outcome results
None listed