Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation

Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04803097

Acronym

capsular

Enrollment

Registered

2021-03-17

Start date

2016-06-01

Completion date

2020-01-01

Last updated

2021-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Capsular Contracture, Implant, Pediatric Cataract

Keywords

capsular outcome, pediatric cataract, posterior capsulorhexis

Brief summary

Lens capsular often changes after pediatric cataract surgery，causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on. The aim of study was to prospectively investigate the capsular outcomes of pediatric cataract surgery with primary intraocular lens (IOL) implantation.

Detailed description

To investigate the capsular outcomes from a case series of children who underwent cataract surgery and primary IOL implantation at the Eye Hospital of Wenzhou Medical University between 2016 and 2019. Took Digital retro-illumination photographs of pediatric eyes at baseline and 6 months, 12 months, and the last visit postoperatively. Compare the capsular outcomes of the posterior capsule opening (PCO) area and visual axis transparent area at those time points, and analysis the correlations between the PCO area and influential factors, such as age at surgery, axial growth, and follow-up duration.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

6 Months to 96 Months

Healthy volunteers

Inclusion criteria

Children (age 0.5\ 8 years) who underwent cataract surgery, posterior capsulorhexis or capsulotomy and anterior vitrectomyand primary IOL implantation at the Eye Hospital of Wenzhou Medical University (Hangzhou, China). The follow-up period was at least 1 year.

Exclusion criteria

Patients with ocular trauma, corneal disorders, glaucoma, preoperative lens luxation or subluxation, membranous cataract, persistent hyperplastic primary vitreous, surgical or postoperative complications such as glaucoma or suspect-glaucoma and synechia, pupils that could not be sufficiently dilated, and those who could not complete follow-ups or did not have clear digital photographs.

Design outcomes

Primary

Measure	Time frame	Description
PCOA	20.74 ± 7.89 months	A comparison of posterior capsular opening areas at the corresponding time points
VATA	20.74 ± 7.89 months	A comparison of visual axis transparent areas at the corresponding time points

Secondary

Measure	Time frame	Description
axial length growth	20.74 ± 7.89 months	The growth of axial length at the corresponding time points

Countries

China

Outcome results