Pancreatic Ductal Adenocarcinoma
Conditions
Keywords
pancreaticoduodenectomy
Brief summary
The primary aim of this population-based study is to investigate how a high resection rate of pancreaticoduodenectomy affects overall survival among patients aged ≥70 years with pancreatic ductal adenocarcinoma. The secondary aim is to determine if a high resection rate of pancreaticoduodenectomy increases perioperative morbidity.
Interventions
OTHERResection rates
All groups are divided into one high- and one low resection rate group depending on percentage of patients with pancreatic ductal adenocarcinoma resected per county and year (first three groups) and resection rate of pancreaticoduodenectomy per 100 000 inhabitants per county (last three groups)
Sponsors
Linkoeping University
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Diagnosed between 1 January 2010 and 31 December 2018 * Registered in the Swedish National Registry for tumours in the pancreatic and periampullary region * Either a diagnosis of pancreatic ductal adenocarcinoma of the pancreatic head or having been resected with pancreaticoduodenectomy
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival | A little more than 10 years (from first patient to vital status) | Overall survival among patients aged 70 years and over with pancreatic ductal adenocarcinoma in the pancreatic head |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Severe complications after pancreaticoduodenectomy | Around 10 years (patients diagnosed between 1 January 2010 and 31 December 2018, latest dismissal from hospital january 2020) | The rate of severe complications among patients aged 70 years and over who had undergone pancreaticoduodenectomy for any reason |
Outcome results
None listed