Obesity
Conditions
Keywords
Cardiac fat, Cardiac function, Aerobic interval training, Cardiac Magnetic Resonance, Vascular health
Brief summary
The overall goal of this project is to the study the effects of an aerobic interval training program on cardiac fat, and its relationship to cardiac function using cardiac Magnetic Resonance Imaging.
Interventions
The aerobic interval training group
Sponsors
Southern Illinois University Edwardsville
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* females, age 18-40 years old, body mass index (BMI) ≥ 30 kg/m2 and \< 39.9 kg/m2, without known metabolic and/or cardiovascular disease
Exclusion criteria
* known CV, metabolic or pulmonary diseases or conditions, muscular-skeletal injuries (i.e. spine, knees, hips or shoulders, taking medications that affect endocrine or cardiovascular function, hypertension, being engaged in moderate intensity exercise more than two times per week or moderate-high intensity training of any type and frequency, being pregnant, cigarette smoking, having non-removable pieces or devices incompatible with DXA and CMR assessment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Cardiac Adipose Tissue (CAT) | 2 assessment points: at baseline and week 5 | CAT will be measured using cardiac Magnetic Resonance |
| Changes in Cardiac Function | 2 assessment points: at baseline and week 5 | Cardiac Function will be measured using cardiac Magnetic Resonance |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Body Composition | 2 assessment points: at baseline and week 5 | Body composition will be measured using dual-energy x-ray absorptiometry |
| Changes in Cardiorespiratory Function | 2 assessment points: at baseline and week 5 | Cardiorespiratory Function will be measured on a treadmill with a metabolic cart |
| Changes in Muscular Strength | 2 assessment points: at baseline and week 5 | Muscular Strength will be assessed through 1 repetition maximum (1RM). |
| Changes in Blood Pressure | 2 assessment points: at baseline and week 5 | Blood pressure will be measured using pulse wave analysis |
Countries
United States
Outcome results
None listed