Skip to content

Effect of Stellate Ganglion Block Combined With Facial Nerve Block on the Treatment of Idiopathic Facial Paralysis

Effect of Stellate Ganglion Block Combined With Facial Nerve Block on the Treatment of Idiopathic Facial Paralysis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04800666
Enrollment
80
Registered
2021-03-16
Start date
2021-03-01
Completion date
2022-03-30
Last updated
2022-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral Facial Palsy

Keywords

Peripheral Facial Palsy, Stellate Ganglion Block, Facial Nerve Block

Brief summary

Peripheral facial palsy is caused by damage to the facial nerve at any site of the peripheral branches after the facial nucleus.Stellate ganglion block is performed to treat peripheral facial palsy because it increases blood flow and promotes nerve regeneration.Facial Nerve Block worked with elimination of local inflammation of nerve and oppression. Facial nerve block is a treatment that inject drugs into the damaged nerve around to eliminate local inflammation and compression of the nerve.

Interventions

PROCEDUREStellate Ganglion Block

Patients underwent a stellate-ganglion block at the anterolateral aspect of the C6 vertebra. After local analgesia (lidocaine 2%), a 22-gauge Quincke needle was placed in the anterolateral aspect of the C6 vertebral body. When the needle contacted the bone, it was drawn back 1 mm. 5 mL of 0·5% ropivacaine was subsequently injected next to the stellate ganglion to produce a sympathetic block.The effect of the stellate-ganglion block on the sympathetic nervous system was confirmed by the presence of Horner's syndrome (ie, facial anhydrosis, enophthalmos, ptosis, swelling of the lower eyelid, miosis, and blood-shot conjunctiva), and an increase in the temperature of the right hand of at least 2°F from baseline.

Operator touching the location of the mastoid, in the external auditory canal just below the front of the mastoid vertical needling.When touch the surface of the mastoid,adjust the needle across the front of the mastoid then slow needling about 1cm.The pin located below the stylomastoid foramen, and then injected drugs 5mL ( mecobalamin injection 1mg;lidocaine 60mg; dexamethasone 10mg )

oral Mecobalamin Tablets tid-8

Sponsors

Zhuan Zhang
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

Diagnosed by clinical and neurological assessment as one-sided simple facial * Age 18 to 75 years * HBGS above Ⅳ * the course of IFP not over 7 days.

Exclusion criteria

* Coagulation dysfunction * plate plate plate shape, quantity or abnormal function * mental system diseases * Gillan-Bahrain syndrome * cancer, mumps, shingles infection, jaw facial pus lymph nodeitis, encephalitis, -cerebral hemorrhage and other diseases * local infection or systemic infectious disease at the puncture site * can not accept to nerve block

Design outcomes

Primary

MeasureTime frameDescription
Change from Baseline House-BrackmannBaseline ,change from baseline House-Brackmann at 3 days,6 days,9 days,14 days,one month,two monthThe House-Brackmann scale is a nerve grading system developed in 1985 by Los Angeles otolaryngologists Dr. John W. House and Dr. Derald E. Brackmann. It is used to characterize the severity of a facial paralysis patient's symptoms.
Change from Baseline SunnybrookBaseline,change from baseline Sunnybrook at 3 days,6 days,9 days,14 days, one month,two monthSunnybrook is a new facial nerve function of subjective assessment system.It is based on both static and dynamic aspects.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026