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Computer-based Training of Face Recollection to Improve Face Recognition in Developmental Prosopagnosia

Characterizing and Remediating Recollection-specific Face Recognition Deficits in Developmental Prosopagnosia

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04799340
Enrollment
60
Registered
2021-03-16
Start date
2021-03-12
Completion date
2025-07-01
Last updated
2022-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Developmental Prosopagnosia

Brief summary

This study will examine the effectiveness of a cognitive training intervention targeting face recollection, repetition lag training, at improving face recognition in Developmental Prosopagnosia.

Interventions

BEHAVIORALcognitive training

training to improve encoding and recognition of faces

Sponsors

Boston VA Research Institute, Inc.
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes

Inclusion criteria

Developmental prosopagnosic participants will be included if they are... * aged 18-90, * have lifelong histories of face recognition difficulties that impact their everyday life (i.e., not associated with some event such as a stroke, seizure, etc) * score significantly below the mean on the famous faces test and Cambridge Face Memory Test

Exclusion criteria

Participants will be excluded from the study if they... * have a history of a significant neurological disorder including hydrocephalus, stroke, moderate to severe traumatic brain injury (TBI), severe neuromuscular diseases, or severe hypoxia due to cardiac arrest. * have impairments that interfere with cognitive performance, such as uncorrected hearing or vision, lack of English proficiency, musculoskeletal or other issues * have psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, chronic intractable obsessive-compulsive disorder, or agoraphobia. * We will exclude individuals who are currently dependent on alcohol or other substances, as this may negatively impact cognitive performance. * We will exclude participants who currently are, or within the last 6 months, participating in a behavioral or pharmacological intervention. * Patients with a history of mild TBI or simple concussion will not be excluded as long as it was \> 6 months ago and as long as they have not had repeated concussions (\>5) * We will include individuals with a diagnosis of ADHD as long as their medication has been consistent for the past 6 months.

Design outcomes

Primary

MeasureTime frameDescription
Cambridge Face Memory Test15 minuteslearning and recognizing novel faces, out of 72 (higher score is better)
Face Recollection15 minutesold/new face recognition test, extracting familiarity and recollection parameters, higher score is better
Face Perception30 minutescomposite of face matching tasks, Cambridge Face perception Test and computerized Benton, higher score is better

Secondary

MeasureTime frameDescription
Self-reported face recognition5 minutesquestionnaire
Face-name learning task15 minutes

Countries

United States

Contacts

Primary ContactJoseph M DeGutis, Ph.D.
degutis@hms.harvard.edu510-734-7705

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026