Adductor Canal Block Versus Patient Controlled Analgesia, in the Surgical Stress Response for Anterior Cruciate Ligament Repair

Impact of Adductor Canal Block, Compared to Patient Controlled Analgesia, in the Surgical Stress Response of Patients Programmed for Traumatic Anterior Cruciate Ligament Repair

Status

Withdrawn

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04797546

Enrollment

Registered

2021-03-15

Start date

2016-09-30

Completion date

2018-11-30

Last updated

2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Stress, Physiological, Surgery

Brief summary

To evaluate the surgical stress response in anterior cruciate ligament repair with an adductor canal block versus patient controlled endovenous analgesia.

Detailed description

Preoperative, 2 hours and 24 hours stress biomarkers will be evaluated in two groups of patients, continous adductor canal block and morphine patient controlled endovenous analgesia.

Interventions

PROCEDUREAdductor Canal Block

Continous peripheral nerve block

DEVICEMorphine Patient Controlled Analgesia

Morphine Patient Controlled Analgesia Delivery System

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Male, * 18-65 years, * traumatic Anterior Cruciate Ligament tear, scheduled for elective arthroscopic repair with Semitendinous-Gracillis technique at first time in the morning, with full articular range, * no other traumatologic lesions.

Exclusion criteria

* denied consent to participate, * chronic steroids user, * diabetes type 1 or 2, * insulin resistance, * concurrent infectious disease, * cognitive failure, coagulopathy, * allergy to study drugs, * surgery scheduled in the afternoon

Design outcomes

Primary

Measure	Time frame	Description
Change of Blood Cortisol from baseline to 24 hours	24 hours	Blood Cortisol will be evaluated preoperatively, 2 hours and 24 hours postoperatively.

Secondary

Measure	Time frame	Description
Change of C Reactive Protein from baseline to 24 hours	24 hours	C Reactive Protein will be evaluated preoperatively, 2 hours and 24 hours postoperatively.
Change of Glycemia from baseline to 24 hours	24 hours	Glycemia will be evaluated preoperatively, 2 hours and 24 hours postoperatively.

Countries

Chile

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026