Comparison Of Outcome Of Lactose Free Formula Milk With Yogurt In Children With Acute Diarrhea

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04796480

Enrollment

Registered

2021-03-15

Start date

2018-06-10

Completion date

2018-12-09

Last updated

2021-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Diarrhea

Keywords

LACTOSE FREE FORMULA MILK, YOGURT

Brief summary

This study was aimed to look at the effect of lactose free formula milk in comparison with home-made plain yogurt in children with acute watery diarrhea.

Detailed description

A randomized controlled trial using non probability consecutive sampling was carried out on 60 children (30 in each group) in Department of Paediatrics Unit I, Services Hospital Lahore. An informed written consent was taken from parents of the children. Ethical issues considered and maintained throughout the study. Then all children were randomly divided in two groups by using lottery method. In group 1; children were given yogurt while in group 2, children were given lactose free formula milk. In both groups, feed was given 5-8 times per day. Patients were followed-up till resolution of symptoms and discharge from hospital.

Interventions

DIETARY_SUPPLEMENTYOGURT

Group 1 was given yogurt

DIETARY_SUPPLEMENTLACTOSE FREE FORMULA MILK

Group 2 was given lactose free formula milk

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Intervention model description

Participants were divided in 2 groups.

Eligibility

Sex/Gender

ALL

Age

4 Months to 24 Months

Healthy volunteers

Inclusion criteria

* Children of age 4-24 months presenting with acute diarrhea * Both gender

Exclusion criteria

* Children on antibiotic therapy within 48 hours prior to presentation * Malnourished children (-2SD as per WHO criteria) * Children with severe dehydration requiring IV fluids * Children \< 4 months of age (as weaning not started yet)

Design outcomes

Primary

Measure	Time frame	Description
Effect of home-made yogurt versus lactose-free milk on mean duration of diarrhea in children with acute diarrhea	6 Months	The effect of home-made yogurt and lactose-free milk in children with acute diarrhea was compared i.e. to check out which one is more suitable to treat diarrhea by measuring the mean duration of diarrhea in hours. The reason behind the effectiveness of yogurt against lactose-free milk is the presence of probiotics within it, which help in recovering of good bacteria population in intestine and so may help in decreasing duration and severity of diarrhea.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026