Autogenous Tooth Bone Graft, Immediate Implant Placement, L-PRF
Conditions
Brief summary
Immediate implant placement into fresh extraction sockets is gaining popularity because of fewer clinical procedures and maintenance of bone architecture compared to conventional methods, thus reducing the treatment time and increasing patient satisfaction. In addition, the survival rate of the immediate implantation is comparable to that of the healed implantation sites. Recently, ATBG made from compromised teeth was applied in bone defects and resulted in a good clinical efficacy. Moreover, it is more accepted by patients to use extracted teeth as a bone graft material, especially in the case of immediate implant placement. In 2020, Kizildağ and coworkers studied the outcome of PRF as an adjunct with ATBG on bone healing in rabbit peri-implant osseous defects. They reported that combination of ATBG with PRF contributed to significantly higher new bone formation and better bone/implant contact in rabbits with peri-implant bone defects. The main hypothesis behind this study is that using L-PRF with ATBG following immediate implant placement could promote stabilization of graft particles and enhance new bone formation with a shorter time. Therefore, the purpose of this study was to compare the clinical and radiographic outcomes of ATBG on bone formation with or without L-PRF around immediately placed dental implants in periodontally compromised teeth.
Interventions
COMBINATION_PRODUCTimmediate implant placement with ATBG and L-PRF
immediate implant placement using ATBG as a graft material, with L-PRF
COMBINATION_PRODUCTimmediate implant placement with ATBG
immediate implant placement using ATBG as a graft material without L-PRF
Sponsors
Dalia Rasheed Issa
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Teeth need to be extracted for periodontal reasons with a defect of labial bone (horizontal or vertical bone defect). * the teeth without acute inflammation. * no uncontrolled systemic disease which is not suitable for implantation. * Good systemic and oral health.
Exclusion criteria
* patients with systemic diseases or medications known to alter healing processes * Psychiatric disorders. * Root canal treated teeth. * patients undergoing or who had undergone radiation therapy and chemotherapy to the head and neck region during 12 months. * patients with para-functional habits. * alcoholics. * drug abusers. * heavy smokers
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical evaluation of bone formation around immediately placed dental implants | 9 months | Changes on bone formation using ATBG with or without L-PRF around immediately placed dental implants in periodontally compromised teeth |
| radiographic outcome around immediately placed dental implants | 9 months | the radiographic outcome of ATBG on bone formation with or without L-PRF around immediately placed dental implants in periodontally compromised teeth |
Countries
Egypt
Outcome results
None listed