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Population Burden of STI and Implication for Intervention in Hong Kong

Population Burden of Sexually Transmitted Infections and Implication for Intervention in Hong Kong

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04793841
Enrollment
1977
Registered
2021-03-11
Start date
2021-05-13
Completion date
2024-12-31
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

STI

Keywords

chlamydia trachomatis, Neisseria gonorrhoeae, human papillomavirus, men who have sex with men, general population

Brief summary

This is a 5-year cross-disciplinary sexually transmitted infection (STI) project involving a) territory-wide and community-based studies (survey and specimen collection); b) simulation of STI transmission dynamics and comparison of STI intervention strategies through mathematical modelling and cost-effectiveness analysis. The aim of this project is to assess the burden and the transmission dynamics of STIs in the general population and men who have sex with men (MSM) in Hong Kong. Around 1300 sexually experienced adults and 900 MSM would be recruited, 100 participants would be invited for individual in-depth interviews. Main outcome measures include STI history and service preference, effectiveness as measured by the proportion of new STI infections (chlamydia, gonorrhoea and human papillomavirus infections) averted above base-case scenario, and incremental cost-effectiveness ratio.

Detailed description

After completion of baseline questionnaire, the participants are invitied for STI self-sampling. If agree, a package of self-sampling kits, instructions, and packaging materials for return post would be delivered to their selected collection points. The second round of self-sampling would be offered at least one year from the first round of self-sampled specimens collected.

Interventions

OTHERself-sampling kits for STI testing in laboratory

participants in both groups will receive self-sampling kits and deliver the collected samples to laboratory for testing

Sponsors

Chinese University of Hong Kong
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* aged 18 or above * ever having sex * normally living in Hong Kong * can communicate in English or Chinese

Exclusion criteria

* failed to provide consent

Design outcomes

Primary

MeasureTime frameDescription
self-reported STI diagnosis in questionnaireup to 2 yearsnumber of STI diagnosis
effectiveness of STI intervention strategies10 yearsincremental cost-effectiveness ratio

Secondary

MeasureTime frameDescription
STI symptom reported in questionnaire12 monthstypes of symptom presentations
willingness to pay for STI testing reported in questionnaire12 monthswillingness to pay (HKD)
prevalence of STI estimated through laboratory testing12 monthsprevalence of chlamydia trachomatis, Neisseria gonorrhoeae and human papillomavirus infections from self-collected samples

Countries

Hong Kong

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026