Skip to content

Establishment of Tongue Image Database and Machine Learning Model for Malignant Tumors Diagnosis

A Multi-center Observational Clinical Study Observing the Differences of Tongue Images Between Patients With Malignant Tumors and Healthy People

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04793672
Enrollment
4100
Registered
2021-03-11
Start date
2020-05-01
Completion date
2024-12-30
Last updated
2026-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malignant Tumor

Keywords

Malignant tumor, Tongue Image

Brief summary

The tongue images of malignant tumors and corresponding healthy people will be collected to establish the tongue image database. Deep learning will be carried out by computer and artificial intelligence to construct the early screening, diagnosis, prognosis and prognosis model of various malignant tumors based on tongue image for the diagnosis and treatment of malignant tumors.

Interventions

OTHERTongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected.

Tongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected.

Sponsors

Zhejiang Cancer Hospital
Lead SponsorOTHER
Sichuan Cancer Hospital and Research Institute
CollaboratorOTHER
Zhejiang Hospital of TCM
CollaboratorUNKNOWN
Wenzhou Medical University
CollaboratorOTHER
Fujian Cancer Hospital
CollaboratorOTHER_GOV
RenJi Hospital
CollaboratorOTHER
Zhejiang Provincial Tongde Hospital
CollaboratorOTHER
Kecheng District People's Hospital
CollaboratorUNKNOWN
Yueyang Central Hospital
CollaboratorOTHER
Shandong Cancer Hospital and Institute
CollaboratorOTHER
Shanxi Province Cancer Hospital
CollaboratorOTHER
Liaoning Cancer Hospital & Institute
CollaboratorOTHER
Harbin Cancer Hospital
CollaboratorUNKNOWN
Yuhang District People's Hospital
CollaboratorUNKNOWN
Hainan Cancer Hospital
CollaboratorOTHER
Zigong Fourth People's Hospital
CollaboratorUNKNOWN
Henan University of Science and Technology
CollaboratorOTHER
The First People's Hospital of Changzhou
CollaboratorOTHER
The First Affiliated Hospital of Soochow University
CollaboratorOTHER
Zhoushan Hospital, Zhejiang
CollaboratorUNKNOWN
Xianju People's Hospital
CollaboratorOTHER
Fenghua District People's Hospital, Ningbo City
CollaboratorUNKNOWN
Shangyu People's Hospital of Shaoxing City
CollaboratorUNKNOWN

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* 18≤age≤80 * Histologically or cytologically confirmed malignant tumor * No prior chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor treatment for malignant tumor * Subject volunteers to join the study, Signs informed consent, has good compliance and can cooperate with follow-up

Exclusion criteria

* Two or more kinds of malignant tumors at the same time * Malignant tumor that has been treated by chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor therapy * Subjects who had other factors that might force them to terminate the research ahead of time, such as the development of other severe disease (including mental disease) that required combined treatment, seriously abnormal laboratory examination value, and family or social factors that might affect the subject safety or experimental data collection, as judged by the researchers

Design outcomes

Primary

MeasureTime frame
The differences of tongue images between patients with malignant tumors and healthy people.1 year
Overall Survival (OS)3 years

Secondary

MeasureTime frame
Disease free survival(DFS)1 year

Countries

China

Contacts

PRINCIPAL_INVESTIGATORXiangdong Cheng, MD

Zhejiang Cancer Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 26, 2026