Acute Right Heart Failure, Peripheral Veins Doppler Ultrasound, Pulmonary Hypertension
Conditions
Brief summary
Occurrence of acute right heart failure (ARHF) remains common during pulmonary hypertension (PH). Right atrial pressure (RAP) invasive measurement is the gold standard to diagnose ARHF in order to improve diuretic treatment management. Existence of indirect signs of ARHF on venous Doppler ultrasound waveform has long been described, but correlation with RAP has not been properly established yet. It is the aim of our study in order to obtain an additional tool to manage ARHF.
Interventions
DIAGNOSTIC_TESTPeripheral veins Doppler ultrasound
Patients undergoing a right heart catheterization for PH diagnosis or annual follow-up in the cardiological unit of the university hospital of Poitiers will be included. A venous Doppler ultrasound will be performed by a vascular physician, with experience in vascular ultrasound imaging, within 4 hours before the right heart catheterization. Morphological parameters of vena cava, and velocimetric parameters of femoral, jugular and supra-hepatic veins will be assessed in order to study their correlation with right auricular pressure value.
Sponsors
Poitiers University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patient (age ≥ 18 years old) * Patient referred to the cardiology department for a right heart catheterization with measurement of RAP, regardless of the indication. * Free subject, without guardianship or curatorship or subordination * People affiliated to or beneficiary of a social security schemes * Informed consent signed by the patient after clear and fair information about the study.
Exclusion criteria
* Minor patient (age \< 18 years) * Refusal to participate in the study * Patient with hemodynamic instability, unable to tolerate a delay in treatment caused by the ultrasound examination. * Patient requiring diuretic treatment within the next 4 hours * Patient with a life expectancy of less than 24 hours. * History of proximal deep venous thrombosis involving the inferior vena cava and/or common iliac veins and/or femoral veins. * History of extrinsic venous compression on the inferior vena cava and/or common iliac veins and/or femoral veins. * Persons who do not benefit from a Social Security scheme or who do not benefit from it through a third party. * Persons benefiting from reinforced protection, namely minors, pregnant and nursing women, persons deprived of liberty by a judicial or administrative decision, persons staying in health or social institutions, adults under legal protection and finally patients in emergency situations.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sensitivity, specificity, positive and negative likelihood ratios of venous stasis index | Inclusion day within 4 hours before the right heart catheterization | Sensitivity, specificity, positive and negative likelihood ratios of venous stasis index\*, measured by Pulsed Doppler on common femoral veins, as a diagnostic criterion for ARHF (defined by RAP ≥10 mm Hg). \* Defined as duration of non-anterograde venous flow during 3 seconds/ 3 seconds |
Countries
France
Outcome results
None listed