Encephalopathy, Multiple Sclerosis, Optic Neuritis
Conditions
Brief summary
3D FLAIR, 3D T1 FAT SAT, coronal T2 and coronal T1 dixon sequences were usually used to assess visual deficits in MRI. Optic nerve examination is preferably performed using a coronal T2 sequence in order to detect a hypersignal suggestive of inflammation whereas brain examination is preferably performed using a 3D FLAIR sequence to highlight signs of spatial dissemination and lesions suggestive of multiple slerosis (MS). Recently, a study based on a small number of patients showed the interest of 3D FLAIR in the detection of the hypersignal of the optic nerve.The objective of this retrospective study is to determine whether a single 3D FLAIR sequence allows simultaneous exploration of the optic nerve and the brain for the positive diagnosis of optic neuropathy and/or MS.
Interventions
DIAGNOSTIC_TESTMagnetic Resonance Imaging
Comparing 3D FLAIR versus Coronal T2-WI MRI in detecting Optic Neuritis
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \> 18 years * Decrease in visual acuity explored in MRI between january 2018 and january 2020
Exclusion criteria
* Past history of episode of Optic neuritis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Detection of optic neuropathies using MRI | 1 hour | MRI comparison of the diagnostic performance of the 3D FLAIR sequence and the T2 coronal in the detection of optic neuropathies. |
Countries
France
Outcome results
None listed