Acute Respiratory Failure
Conditions
Keywords
Covid19, Acute Respiratory Failure, Ultrasound, Checklist, Emergency, Diagnosis
Brief summary
The aim of the study is to evaluate if a check-list including lung ultrasonography can help to identify the etiology of the acute respiratory failure of patients managed at the emergency room. Adult patients admitted to the emergency room for acute respiratory failure will be offered the study. The emergency physician will perform a systematic examination using a checklist, including pulmonary embolism prediction scores, structured clinical examination and lung ultrasound, in order to establish a diagnostic hypothesis. A diagnostic hypothesis will be made after completion of the checklist. The emergency physician can perform additional examinations and treatment after completion of the checklist. The final diagnosis will be checked by an adjudication committee which will have all the documents established during the emergency room consultation and any hospitalization following this hospitalization. The main outcome will be the concordance rate between the diagnosis after the check-list and the final diagnosis.
Interventions
OTHERcheck-list including lung ultrasound
The investigator will follow the checklist which includes the collection of anamnestic data and clinical signs, the performance of a pulmonary embolism clinical probability score and a cardiopulmonary ultrasound with count -standardized rendering. After completing this checklist, the investigator will note their diagnosis (list of proposals on the data collection sheet), the treatments started (closed list of therapeutic classes). If he orders other tests, he will write them down and then note the diagnosis made and the treatments prescribed after obtaining the results of these tests. The therapeutic management of patients compared to the usual care in the respective departments may be modified depending on the results of the cardiopulmonary ultrasound . The emergency physician may initiate therapy before the results of additional examinations that he would have usually performed without cardiopulmonary ultrasound.
Sponsors
Centre Hospitalier Metropole Savoie
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient with acute respiratory failure table (SpO2 90% in ambient air or need more than 3 L/min of oxygen to have SpO2 \> 92% AND/OR signs of respiratory struggle sign AND/OR respiratory rate control \> 25 cycles/minute AND/OR cyanosis) * Over 18 years old
Exclusion criteria
* Pregnant, Parturising or Breastfeeding Women * Patient who has already participated in the study in the previous 7 days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Agreement between the etiology retained after using the checklist and the diagnosis retained by an adjudication committee after analysis of the entire patient file. | 1 month after inclusion | The adjudication committee will meet all 35 inclusions to determine the diagnosis of each patient after analysis of the complete anonymized file which will be provided by locol investigator one month after inclusion. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Analysis of the diagnosis retained after the checklist in patients with a final diagnosis of COVID-19; analysis of the final diagnosis in patients with a diagnosis of COVID-19 evoked after the checklist | One month after inclusion | The adjudication committee will meet periodically after analysis of the complete anonymized file to check the COVID diagnosis. |
| Collection of treatments started only after completion of the checklist and verification of its suitability for the diagnosis selected | at one day | All the treatments started only after completion of the checklist wil be collected prospectively and their appropriateness will be checked. |
| Collection of additional examinations possibly performed in the emergency unit after the completion of the checklist | at one day | All additional examinations performed after the completion of the checklist will be collected |
| Comparison of treatments introduced after completion of the checklist and after the other additional examinations performed at the emergency room | at one day | all treatments delivered after the completion of the checklist and after complementary exams will be collected and classified into therapeutic families (antibiotics, diuretics). |
| Delay between completion of the checklist and obtaining the results of any other examinations | At one day | Time between the completion of the checklist and obtaining the last result of the other examinations performed at the emergency room (except for bacterial culture) |
Countries
France
Outcome results
None listed