Chronic Heart Failure (CHF)
Conditions
Keywords
Cardiac rehabilitation, Chronic Heart failure, Physical function, Cameroon
Brief summary
CARECA-CHF study is a non-randomized, prospective, single-arm study, enrolled ambulatory patients with stable chronic heart failure \[New York Heart Association (NYHA) class II/III\]. Patients will be followed-up during a period of 06-08 weeks. The aim of this study is to assess the effect of a cardiac rehabilitation program on patients with stable chronic heart failure in Yaoundé, Cameroon.
Detailed description
CARECA-CHF study is a non-randomized, prospective, single-arm study, multicentric study. Patients with stable chronic heart failure \[New York Heart Association (NYHA) class II/III\] will be enrolled ambulatory. The program will take place during a period of 06-08 weeks. The aim of this study is to assess the effect of a cardiac rehabilitation program on patients with stable chronic heart failure in a resource-limited country.
Interventions
OTHERCHF Patients
Cardiac rehabilitation program on CHF patients on 06-08 weeks. Program will include: physical aerobic re-training, therapeutic education on CHF, psychological follow-up, nutritional education
Sponsors
Yaounde Central Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Patients with stable CHF in stage II or III of the New York Heart Association.
Eligibility
Sex/Gender
ALL
Age
21 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients with stable chronic heart failure confirmed by a cardiac ultrasound and whose severity is rated stage II or III of NYHA followed at Yaoundé central hospital and Yaoundé general hospital; * Stable under treatment; * Whose cardiac ultrasound is less than six months old; * Having given his free and informed consent.
Exclusion criteria
* Poor adherence to the cardiac rehabilitation program activities; * Patients lost insight the program; * Withdrawal of informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of VO2 max | 8 weeks | Variation of VO2 max at baseline and the end of the study |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Variation of duration of exercise and maximum load | 8 weeks | variation in duration of exercise and maximum load expressed by watt power |
| Variation in level of anxiety and depression; | 8 weeks | Difference in level of anxiety and depression assessed by a questionnaire |
| Change in quality of life assessed by the Minnesota Living With Heart Failure Questionnaire (MLWHFQ) | 8 weeks | Change in quality of life assessed by the Minnesota Living With Heart Failure Questionnaire (MLWHFQ) Minnesota Living With Heart Failure Questionnaire score at Week 8 adjusted for baseline |
| Variation of time-domain heart rate variability (HRV) parameters | 8 weeks | Variation of time-domain heart rate variability parameters before and after the intervention |
| Variation in 6-minute walk test (6MWT) distance | 8 weeks | Variation in 6MWT in meter distance from the baseline to week 6 or 8. By using pedometer |
| Variation of index hypopnea-apnea index | 8 weeks | Variation of variation of index hypopnea-apnea after 6-8 weeks of aerobic training. |
| Variation of sleep quality index | 8 weeks | variation of sleep quality index by Pittsburg questionnaire |
| Variation of nocturnal saturation | 8 weeks | Variation of nocturnal saturation by oxymeter |
| Non adherence | 8weeks | evaluation of non adherence by questionnaire at the end of the study |
| Variation of frequency-domain HRV parameters | 8 weeks | variation of frequency-domain HRV parameters before and after the intervention. Variation of frequency-domain HRV parameters (HF, LF, LF/HF) before and after the intervention. |
Countries
Cameroon
Outcome results
None listed