Initial CT Findings and CO-RADS Stage in COVID-19

Comparison of Initial CT Findings and CO-RADS Stage in COVID-19 Patients With PCR, Inflammation and Coagulation Parameters in Diagnostic and Prognostic Perspectives

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04789447

Enrollment

895

Registered

2021-03-09

Start date

2021-03-04

Completion date

2021-05-06

Last updated

2021-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19, Pneumonia, Viral, SARS-CoV Infection

Keywords

COVID-19, SARS-CoV2 RT-PCR Testing, Thorax, Computerized Tomography, Mortality, Prognosis

Brief summary

This study aims to determine whether patients with different real-time reverse transcriptase-polymerase chain reaction (PCR), chest computed tomography (CT) and laboratory findings have different clinical outcomes.

Detailed description

This study aims to determine the rates of PCR positivity and CT findings in hospitalized patients with a diagnosis of COVID-19, to determine whether there is a difference in mortality and need for ICU between patients grouped according to the PCR positivity and presence of CT findings, and to evaluate the effect of the CO-RADS stage on these outcomes. Moreover, it is to compare the effects of inflammation and coagulation markers and CO-RADS stage on the severity of the disease

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Aged 18 years and over, * Having SARS-CoV-2 RT-PCR test and chest CT examinations performed at the time of application or within 24 hours after admission * RT-PCR positivity in nasopharyngeal swabs sample, and/or the presence of clinical and laboratory findings of SARS-CoV-2 infection and/or the presence of COVID-19-compatible radiological findings in chest CT, and being diagnosed with COVID-19

Exclusion criteria

* Patients with negative SARS-CoV-2 PCR test, pneumonia on CT but not given Covid-19 treatment by not considering Covid-19 by their doctor will not be included. * Patients whose data are not available * Patients with poor CT image quality * Patients who were transferred to another hospital

Design outcomes

Primary

Measure	Time frame	Description
mortality	up to 30 days	mortality during hospitalization and within 14 days after hospitalization

Secondary

Measure	Time frame	Description
need for intensive care	up to 30 days	need for intensive care during hospitalization and within 30 days after hospitalization
need for intenvasive mechanical ventilation	up to 30 days	need for intenvasive mechanical ventilation during hospitalization and within 30 days after hospitalization

Countries

Turkey (Türkiye)

Outcome results