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Reconstruction of Digital Nerve Lesions With Muscle-in-Vein Conduits

Outcome After Reconstruction of 43 Digital Nerve Lesions With Muscle-in-Vein Conduits

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04788030
Enrollment
37
Registered
2021-03-09
Start date
2008-01-01
Completion date
2021-01-31
Last updated
2021-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral Nerve Injury Upper Limb

Brief summary

Muscle-in-vein conduits (MVCs) provide an alternative for bridging digital nerve defects when tension-free suture is not possible. Low donor site morbidity and absence of additional costs are favorable advantages compared to autografts or conduits. 37 patients with 43 defects of proper palmar digital nerves were retrospectively enrolled. Primary repair by MVCs was performed in 22 cases while 21 underwent secondary reconstruction. Recovery of sensibility was assessed by static and moving two-point discrimination (2PDs, 2PDm) and Semmes-Weinstein monofilaments (SWM). Results were compared with contralateral side serving as intraindividual control. Outcome data were stratified according to international guidelines and evaluated for differences in terms of age, gap length, time of reconstruction and concomitant injuries.

Interventions

Nerve bridging with muscle-in-vein conduits

Sponsors

BG Trauma Center Tuebingen
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
6 Years to 72 Years
Healthy volunteers
No

Inclusion criteria

\- Patients with reconstruction of digital nerves with muscle-in-vein conduits

Exclusion criteria

* Subtotal or total amputations * pre-existing neurological disorders (e.g. polyneuropathy) * symptoms of nerve entrapment

Design outcomes

Primary

MeasureTime frame
Two-point discriminationSix months after reconstruction or later
Semmes-Weinstein-Monofilament testSix months after reconstruction or later

Secondary

MeasureTime frame
AgeBaseline
Gap lengthBaseline
Time of reconstructionBaseline
Concomitant injuriesBaseline

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026