Parkinson Disease
Conditions
Keywords
Parkinson's disease, Virtual reality, Exergame
Brief summary
The study aimed to investigate the effect of applying cognitively challenging exergames using fully immersive virtual reality in patients with Parkinson's disease.
Detailed description
It has been reported that dual-task training involving both cognitive and physical functions helps improve walking speed during dual-task performance without increasing the fall risk in patients with Parkinson's disease (PD). Compared with conventional physical therapy, there are studies that dual-task training significantly improved walking speed and stride in PD patients. In addition, a systematic review study has been reported that it helps to improve balance and cognitive function when dual-task training is performed for patients with neurological diseases including Parkinson's disease. Virtual reality is expected to promote functional recovery in patients with neurological disorders in terms of providing an enriched environment, goal-directed tasks and repetition, and inducing interest and motivation. Therefore, the study aimed to investigate the effect of applying cognitively challenging exergames using fully immersive virtual reality in patients with PD.
Interventions
A total of 10 sessions were held for 30 minutes, 2 to 3 times a week for exergames using fully immersive virtual reality under the assistance of an occupational therapist.
Sponsors
Seoul National University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Clinically diagnosed as idiopathic Parkinson's disease * Modified Hoehn & Yahr stage 2, 2.5, or 3
Exclusion criteria
* Moderate to severe cognitive dysfunction with Mini-mental State Examination score \< 19 * Severe dyskinesia or severe on-off phenomenon * Plan to adjust medication at the time of screening * Other brain diseases such as stroke, brain tumor, etc * History of seizure * Vestibular disease or paroxysmal vertigo * Other comorbidities that make it difficult to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physical dual-task interference (%) in Timed-up & go test | at study completion, an average of 1 month |
| Cognitive dual-task interference (%) in Timed-up & go test | at study completion, an average of 1 month |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Timed-up & go test (sec): cognitive dual-task | at study completion, an average of 1 month | — |
| Timed-up & go test (sec): physical dual-task | at study completion, an average of 1 month | — |
| The Unified Parkinson's Disease Rating Scale | at study completion, an average of 1 month | The higher the score, the more negative the result |
| Berg balance scale | at study completion, an average of 1 month | The higher the score, the more positive the result |
| Trail making test | at study completion, an average of 1 month | — |
| Digit span test | at study completion, an average of 1 month | — |
| New Freezing of Gait Questionnaire (NFOGQ) | at study completion, an average of 1 month | — |
| Stroop test | at study completion, an average of 1 month | — |
| Timed-up & go test (sec): single task | at study completion, an average of 1 month | — |
Other
| Measure | Time frame |
|---|---|
| Simulator sickness questionnaire (SSQ) | at 1st session (an average of 3 days) and at study completion (an average of 1 month) |
Countries
South Korea
Outcome results
None listed