Risk Factors for COVID-19 Mortality

Risk Factors for COVID-19 Mortality: a Prospective Observational Study

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04786808

Acronym

RF-COVID

Enrollment

200

Registered

2021-03-08

Start date

2021-01-15

Completion date

2021-11-07

Last updated

2021-11-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome, COVID-19 Virus Infection, Population at Risk

Brief summary

COVID-19 pandemic has deeply burdened hospitals all over the world. A two-stage disease has been hypothesized due to quick worsening of clinical status after 7-10 days from the beginning of first symptoms, generally flu-like symptoms. Predicting clinical worsening could help to address major efforts towards higher risk patients. During the last year most observational studies, generally retrospective, has been conducted, identifying some risk factors such as age, obesity, male gender, cardiovascular disease, COPD, diabetes etc. The study goal is to collect systematically a variegate amount of clinical, biometric, laboratory and radiological data from patients admitted to the Emergency Medicine Ward of Piacenza Hospital (Italy), in order to prospectively analyze what characteristics are associated to higher risk of mortality.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Admission to the Emergency Medicine Ward from the Emergency Department of Piacenza Hospital (Italy) * Confirmed COVID-19 diagnosis through molecular test obtained from nasal-pharyngeal swabs in the Emergency Department * Age above 18

Exclusion criteria

* inability to obtain an informed consent due to neurological conditions. * patient's refusal to sign the informed consent * inability of researchers to recruit the patient in the first 24 hours from the admission.

Design outcomes

Primary

Measure	Time frame	Description
Mortality rate	28 days after admission	Number of patients who die for any cause in the first 28 days after admission

Secondary

Measure	Time frame	Description
Need of invasive ventilation	15 days after admission	Number of patients who need invasive ventilation in the first 15 days after admission

Countries

Italy

Outcome results