Prolactin Hormone in Oral Lichen Planus

Prolactin Hormone in Oral Lichen Planus Tissue Samples

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04785703

Enrollment

Registered

2021-03-08

Start date

2020-06-19

Completion date

2020-12-10

Last updated

2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Lichen Planus

Brief summary

Oral lichen planus (OLP) is one of the most common mucosal diseases with autoimmune etio-pathogenesis with involvement of various cytokines similar to psoriasis.It generally occurs more commonly in females, in a ratio of 3:2. prolactin (PRL),It is a peptide hormone that has a role in autoimmune related diseases like systemic lupus erythematosus and , rheumatoid Artheritis. The role of PrL in OLP pathogenesis was never investigated.the aim of this study is to investigate the expression of PRL receptors in tissue biopsies of OLP patients.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* patients with oral lichen planus * systemically healthy

Exclusion criteria

* oral lichenoid lesions

Design outcomes

Primary

Measure	Time frame	Description
prolactin receptors expression in oral mucous membrane	24 hours	immuno-histochemistry

Countries

Egypt

Outcome results