Bronchus Anastomosis, Bronchus Stump, Tissue Oxygenation
Conditions
Brief summary
The aim of this study is to find out whether hyperspectral imaging enables bronchus stump and bronchus anastomosis oxygenation.
Detailed description
The bronchus before lung resection and the bronchus stump or bronchus anastomosis, respectively, are investigated. The hyperspectral imaging camera head is placed and aligned over the surgical (camera and object distance: 30 cm for all measurements). The Field of view is illuminated by 8 halogen spots (20 W each) and 100 wavelengths in the wavelength range from 500 to 1000 nm were applied. The software calculates the tissue oxygenation \[%\] , organ-hemoglobin-index, near-infrared-Index and the tissue-water-index of the investigated tissue. The study was designed to investigate tissue oxygenation in the superficial (app. 1mm) and deeper layers (app. 4-6mm) of the bronchus before and after lung resection.
Interventions
DEVICEHSI
diagnostic hyperspectral imaging
Sponsors
LungenClinic Grosshansdorf
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* lung resection or other resection via thoracotomy
Exclusion criteria
* Restriction of the ability to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygenation: Bronchus before lung resection | directly before lung resection | Tissue perfusion of the bronchus before lung resection: Oxygenation (StO2) in %: Relative O2 saturation of the blood in superficial tissue layers (penetration depth: approx. 1 mm) |
| Oxygenation: Bronchus stump or bronchus anastomosis after lung resection | 10-15 minutes after lung resection | Tissue perfusion of the bronchus stump or bronchus anastomosis after lung resection: Oxygenation (StO2) in %: Relative O2 saturation of the blood the in superficial tissue layers (penetration depth: approx. 1 mm) |
| Near Infrared Perfusion Index: Bronchus before lung resection | directly before lung resection | Tissue perfusion of the bronchus before lung resection: Near Infrared Perfusion Index: Tissue perfusion in deeper tissue layers (penetration depth: 4-6mm) |
| Near Infrared Perfusion Index: Bronchus stump or bronchus anastomosis after lung resection | 10-15 minutes after lung resection | Tissue perfusion of the bronchus stump or bronchus anastomosis after lung resection: Near Infrared Perfusion Index: Tissue perfusion in deeper tissue layers (penetration depth: 4-6mm) |
| Tissue-Hemoglobin index: Bronchus before lung resection | directly before lung resection | Tissue perfusion of the bronchus before lung resection: Tissue-Hemoglobin index: Existing hemoglobin distribution in the tissue |
| Tissue-Hemoglobin index: Bronchus stump or bronchus anastomosis after lung resection | 10-15 minutes after lung resection | Tissue perfusion of the bronchus stump or bronchus anastomosis after lung resection: Tissue-Hemoglobin index: Existing hemoglobin distribution in the tissue |
| Tissue-Water-Index: Bronchus before lung resection | directly before lung resection | Tissue perfusion of the bronchus before lung resection: Tissue-Water-Index: Existing water distribution in the tissue |
| Tissue-Water-Index: Bronchus stump or bronchus anastomosis after lung resection | 10-15 minutes after lung resection | Tissue perfusion of the bronchus stump or bronchus anastomosis after lung resection: Tissue-Water-Index: Existing water distribution in the tissue |
Countries
Germany
Outcome results
None listed