Pediatric Cancer
Conditions
Keywords
pediatrics, neoplasms, gait
Brief summary
Cancer incidence, which is recognized as the leading cause of death in children worldwide, is gradually increasing. Most studies on children who survive cancer show that the disease and its treatment have side effects and long-term late effects on the musculoskeletal system, physical function, gait and cognitive skills. Therefore, dual task gait performance, in which cognitive and motor tasks are performed simultaneously, may be affected in pediatric oncology patients. The aim of this study is to compare gait performance in single and dual task conditions in pediatric oncology patients with healthy controls.
Detailed description
Cancer incidence, which is recognized as the leading cause of death in children worldwide, is gradually increasing. About 300,000 children aged 0 to 19 are diagnosed with cancer each year, according to the international study where the International Agency for Research on Cancer collected data on neoplasms (malignant and non-malignant) diagnosed in individuals under 20 years of age between 2001-2010. Most studies on children who survive cancer show that the disease and its treatment have side effects and long-term late effects on the musculoskeletal system, physical function, gait and cognitive skills. According to the study of Beulertz et al. (2016), active ankle dorsiflexion limitation, gait disturbances and decrease in walking efficiency were observed in all pediatric oncology patients, which have an important role in walking, not limited to children with bone tumors and central nervous system tumors.Intensive chemotherapy (eg methotrexate) and the use of radiation are thought to cause damage to cortical and subcortical white matter, resulting in late effects. Symptoms consistent with attention deficit disorder and mental processing speed, working memory, executive function and memory deficits put cancer survivors at an intellectual and academic disadvantage. Therefore, dual task gait performance, in which cognitive and motor tasks are performed simultaneously, may be affected in pediatric oncology patients. The aim of this study is to compare gait performance in single and dual task conditions in pediatric oncology patients with healthy controls.
Interventions
OTHERGait assessment (single)
The single walk will be evaluated with a 10-meter walking test and a G-Walk portable device.
OTHERDual task gait assessment (motor+motor)
The dual task gait, 10-meter walking test and a motor (carrying a full water glass) will be combined with the task and evaluated with the G-Walk portable device.
OTHERDual tak gait assessment (motor+cognitive)
The dual task gait will be combined with a 10-meter walking test and a cognitive (1-back test) task and evaluated with the G-Walk portable device.
Sponsors
Afyonkarahisar Health Sciences University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Years to 18 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy control group: * Being in the age range of 6-18, * To be physically, cognitively and mentally healthy, * Open to communication enough to understand questions, * Speaking and understanding Turkish, * Approval has been obtained from the child and his / her family for the study and who agrees to participate in the study, Case group: * Able to walk alone without any walking aid, * Open to communication enough to understand questions, * Speaking and understanding Turkish, * Approval has been obtained from the child and his / her family for the study and who agrees to participate in the study, * Children between the ages of 6-18 will be included in the study
Exclusion criteria
Healthy control group: * Any orthopedic or neurological impairment that would prevent walking; * Having any mental disability that prevents cognitive task Case group: * Staying in an isolated room or having risk of infection (neutropenic, etc.), * Any orthopedic or neurological impairment that could prevent walking; * Having any mental disability that prevents cognitive task, * Individuals with malignant hypertension or unstable heart disease (eg congestive heart failure) will not be included in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| gait speed | 20 minutes | Gait speed is the time one takes to walk a specified distance on level surfaces over a short distance. |
| cadence | 20 minutes | Cadence is the rate at which a person walk, expressed in steps per minute. The average cadence is 100 - 115 steps/min. |
| stride length | 20 minutes | Stride length is defined as the distance between successive ground contacts of the same foot. |
Countries
Turkey (Türkiye)
Contacts
Primary ContactEMEL TAŞVURAN HORATA, PhD
Outcome results
None listed