Subconjunctival Bupivacaine in Strabismus Surgery

The Effect of Subconjunctival Bupivacaine Injection in Squint Surgery for Postoperative Analgesia

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04782960

Enrollment

Registered

2021-03-04

Start date

2021-04-30

Completion date

2021-05-31

Last updated

2021-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Local

Keywords

Subconjunctival bupivacaine., Strabismus surgery., Postoperative analgesia.

Brief summary

This study aimed to assess the effectiveness of the Subconjunctival bupivacaine on postoperative pain in Strabismus surgery under general anaesthesia.

Detailed description

40 patients will schedule for elective Strabismus surgery under general anaesthesia and randomly allocated into two groups to receive Subconjunctival 0.5%Bupivacaine group(B) or Subconjunctival placebo 0.9% normal saline group at the end of the surgery and assess the postoperative pain at 0th,30th, 60th,2nd h, 4h,6h,12h,24h.and post operative nausea and vomiting.

Interventions

DRUGIocal anaesthetic bupivacaine

Local anaesthetic Subconjunctival bupivacaine

DRUGPlacebo

0.9 saline

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

14 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* All patients aged 14 \_30 years old with body mass index 18\_28kg/m. * American Anaesthesiologist Association physical states I,II. * singed informed consent to participate in the study and were scheduled for strabismus operations under general anaesthesia.

Exclusion criteria

* were patients with chronic pain. * ocular hypertension. * inability to communicate. * history of hematological disease. * allergy to local anesthetic drugs.

Design outcomes

Primary

Measure	Time frame	Description
Visual analog scale (VAS) pain score	5 minutes after extubation	Range, 0\_10;0,no pain ;10,worst pain

Secondary

Measure	Time frame	Description
Nausea and vomiting	24 hours postoperatively	Operation related side effect

Other

Measure	Time frame	Description
Patient satisfaction	24 hours postoperatively	Will be evaluated according to satisfaction score (poor=0, fair=1, good=2, excellent=3)
Visual analog scale (VAS) pain score	30 minutes after extubation	Range, 0\_10;0,no pain ;10,worst pain

Contacts

Primary ContactAbeer Sh Goda

Asg06@fayoum.edu.eg01005151706

Backup ContactAmr H Mahmoud, Msc

Ah1240@fayoum.edu.eg01004349592

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026