S3 Root Pulsed Radiofrequency Added to Superior Hypogstric Plexus Block

the Added Analgesic Effect of S3 Root Pulsed Radiofrequency to Superior Hypogastric Plexus Block in Pelvic Cancer Pain. a Controlled, Randomized Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04782206

Enrollment

Registered

2021-03-04

Start date

2021-03-15

Completion date

2022-05-01

Last updated

2021-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Cancer, Pain, Chronic

Keywords

pelvic cancer pain, superior hypogastric plexus block, pulsed radiofrequency

Brief summary

The investigators hypothesis that adding pulsed radiofrequency neuromodulation at S3 nerve root to superior hypogastric plexus chemical neurolysis improves analgesia in patients with chronic pelvic cancer pain.

Interventions

PROCEDUREsuperior hypogastric plexus block

superior hypogastric plexus chemical neurolysis

PROCEDUREpulsed radiofrequency at S3 root plus superior hypogastric plexus block

pulsed radiofrequency neuromodulation at S3 root plus superior hypogastric plexus chemical neurolysis

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Masking description

double-blinded

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* pelvic cancer patients * with pelvic pain not responding to oral analgesic medications * side effects of oral analgesic medications

Exclusion criteria

* patients with metastatic cancer disease * patients with significantly impaired organ functions * patients with bleeding diathesis * patients with mental disabilities

Design outcomes

Primary

Measure	Time frame	Description
pain intensity	from 30 min. after procedure to 2 months after it	Visual Analogue Scale post-procedure

Secondary

Measure	Time frame	Description
complications	during the block procedure and within the first 24 hours after the block	including transient paresthesia, rectal puncture, vascular penetration of one of the pelvic vessels, hematoma, infection, dural puncture, bowel/bladder dysfunction, pain on injection, hypotension from the sympathetic block or any other complication
procedure time	during the block procedure	The time required to perform the block
Total oral analgesic consumption	in the first 24 hours after procedures and at 1,2,4 weeks and 2 months visits after it	total MST consumption

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026