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Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease

Multicenter Results of Mitral Valve Surgery in Patients With Rheumatic Heart Disease

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04780607
Enrollment
4000
Registered
2021-03-03
Start date
2011-01-01
Completion date
2024-04-01
Last updated
2021-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease

Keywords

rheumtic heart disease, mitral valve surgery

Brief summary

rheumatic heart disease remains the majority valvular disease in low and middle income countries, which mostly affected mitral valve, surgical treatment is the most effective strategy to improve the outcomes of middle or late-stage RHD patient, however, whether mitral valve repair surgery is superior to replacement or other evolving interventional device remains controversial, this study aims to investigate the results of repair surgery compared with replacement or other treatment strategy from international multicenters.

Interventions

different repair techniques to construct rheumatic mitral valve lesion

Sponsors

Beijing Anzhen Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* 1、rheumatic heart disease 2、mitral valve disease 3、combined with other heart valve disease(aortic valve, tricuspid valve, pulmonary valve) 4、patients underwent initial mitral valve surgery or intervention

Exclusion criteria

* 1、congenital heart disease degenerative heart valve disease 2、isolated aortic valve or tricuspid valve, pulmonary valve disease( doesn't affect mitral valve ) 3、patients received more than 1 time mitral valve operation

Design outcomes

Primary

MeasureTime frameDescription
all-cause mortality2011-2024death from any cause

Countries

China

Contacts

Primary Contactxu meng, MD
mengxu191116@163.com
Backup Contactjintao fu, MD, postdoctor
doctorfu0709@126.com

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026