Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection, Gastric Neoplasm, Colonic Neoplasms, Esophageal Neoplasms, Duodenal Neoplasms
Conditions
Keywords
Endoscopic mucosal resection (EMR), Endoscopic submucosal dissection (ESD), Endoscopic full thickness resection (EFTR), Colorectal ESD, Colorectal EMR
Brief summary
The study aims to retrospectively investigate the endoscopic resection procedures of cancerous and precancerous lesions of the upper and lower digestive tract in order to evaluate the efficacy and safety outcomes and to compare different resection techniques. In particular, the resection techniques investigated will be mucosectomy, en bloc and piecemeal, endoscopic submucosal dissection (ESD) and its variants, full-thickness resection. The anatomical districts involved will be the esophagus, stomach, duodenum, colon and rectum.
Interventions
PROCEDUREEndoscopic resection
The endoscopic resection is the procedure that allows to remove cancerous or precancerous conditions of digestive tract. Endoscopic resection can be preformed by several techniques: 1. Endoscopic mucosal resection (EMR): it allows to remove mucosal lesions 2. Endoscopic submucosal dissection: it allows to remove mucosal lesions that involved submucosal layer and large lesions 3. Full-thickness resection: it allows to remove infiltrating lesions by the resection of a little piece of the entire gastrointestinal wall
Sponsors
Azienda USL Reggio Emilia - IRCCS
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* 18 years or older * all patients who have undergone endoscopic resection of an upper or lower digestive tract tumor
Exclusion criteria
* age under 18 * inability to provide informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| en bloc resection rate | one month | the en bloc resection is the ability to remove the neoplasia in a single piece |
| complete resection rate | one month | the complete resection is the ability to remove the neoplasia with clear margins (R0) |
| recurrence rate | one year | recurrence is the recurrence of the neoplasm at the resection site during follow-up |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| adverse events rate | one month | complication rate, early or late, related to the procedure used for endoscopic resection |
| costs | one month | evaluation of the costs incurred to perform the endoscopic resection |
Countries
Italy
Contacts
Primary ContactPaolo Cecinato, MD
Outcome results
None listed