Parasternal Intercostal Muscle Thickness, Weaning From Mechanical Ventilation
Conditions
Keywords
mechanical ventilation, parasternal muscle thickness
Brief summary
Assessment of the the parasternal intercostal muscles thickness by the ultrasonography as a weaning predictor of the mechanically ventilated patients
Detailed description
impact of parasternal muscle thickness on the weaning process of the mechanically ventilated patients in ICU
Interventions
DIAGNOSTIC_TESTParasternal intercostal muscles thickness ultrasound indicies
Parasternal intercostal muscles thickness ultrasound indicies includes: * Parasternal Intercostals Thickness Fraction. * Parasternal Intercostals Thickness at the End of Inspiration. * Parasternal Intercostals thickness at the End of Expiration.
Sponsors
Wesameldin Abelrahman Soltan
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Any patient invasively mechanically ventilated at least 24 hours on a pressure support mode who is clinically stable and ready to undergo a spontaneous breathing trial. All patients will be: * Alert. * Afebrile. * Adequate cough with absence of excessive tracheobronchial secretion. * Fraction of inspired oxygen (FIO2) of \<50%. * PEEP ≤8 cmH2O. * PaO2/FiO2 \> 150. * pH ≥7.35 and ≤7.45. * Respiratory rate (RR) ≤35 breaths/min. * Hemodynamically stable in the absence of vasopressors. * Stable metabolic and endocrinal status. * Euglycemic state. * Adequate mentation (no sedation or stable neurologic patient).
Exclusion criteria
Diaphragmatic paralysis (detected by ultrasonography).Patients&Methods. 6 * Pregnant women. * Age: \>= 18 years. * Surgical dressings over measurement point which would preclude ultrasound exam. * Underweight patients (Body mass index \<18.5 kg/m2). * Morbidly obese patient (Body mass index ≥ 40 kg/m2). * Primary neuro-muscular diseases. * Central coditions with depressed central respiratory drive (encephalitis, and brainstem haemorrhage/ischaemia). * Repiratory conditions with reduced pulmonary compliance (interstitial lung disease, pulmonary hemorrhage, and diffuse pulmonary infiltrates) or reduced chest wall compliance (kyphoscoliosis). * Cardiac conditions with high risk of weaning induced pulmonary edema (congestive heart failure, cyanotic heart diease, pulmonary hypertension, and ischemic heart diease). * Addict patients. * Patients with psychiatric disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the thickness fraction of the parasternal intercostal muscle as a predictor of successful spontaneous breathing trials | Before the start spontaneous breathing trial | The primary outcome is to assess the change of the parasternal intercostal muscles thickness at end of expiration and end of inspiration to verify the thickness fraction of the parasternal intercostal muscle as a predictor of successful spontaneous breathing trials. |
Countries
Egypt
Contacts
Primary ContactWesameldin A Soltan, M.D.
Outcome results
None listed