Effect of Smokeless Tobacco on Anterior Segment

Evaluation of the Effect of Smokeless Tobacco on Anterior Segment Parameters

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04776863

Enrollment

107

Registered

2021-03-02

Start date

2020-03-01

Completion date

2020-11-30

Last updated

2021-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Manifestations, Tobacco Chewing Toxicity, Tobacco; Use, Harmful

Keywords

Optical biometry, pupillar diameter, smokeless tobacco

Brief summary

Observational, comparative, cross-sectional study

Detailed description

To evaluate the acute and chronic effects of smokeless tobacco (ST) on the anterior segment parameters using optical biometry. Observational, comparative, cross-sectional study Place and Duration of Study: Department of Ophthalmology, Kahramanmaras Sutcu Imam University. The study included 53 right eyes of 53 subjects (study group), who used ST and 54 right eyes of 54 healthy subjects without ST (control group). Following a full ophthalmological examination, baseline measurements were taken with optical biometry and these measurements were repeated at 5, 30 and 60 mins after using ST.

Interventions

DEVICEoptical biometry measurement

The measurements of the individuals using smokeless tobacco and those who do not were taken by optical biometry.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

26 Years to 49 Years

Healthy volunteers

Inclusion criteria

* A subject who use ST * A subject who was not using ST

Exclusion criteria

* Refractive disorder * Systemic chronic disease (diabetes, hypertension, neurological, etc.) * Ocular trauma * Ocular surgery * Glaucoma * Optic disc abnormalities * Congenital anomaly

Design outcomes

Primary

Measure	Time frame	Description
Central Corneal Thickness (CCT)	Baseline to 60 minutes after intervention	Change in Central Corneal Thickness (CCT
Axial Length (AL)	Baseline to 60 minutes after intervention	Change in Axial Length (AL)
Anterior chamber deep (ACD)	Baseline to 60 minutes after intervention	Change in Anterior chamber deep (ACD)
Lens thickness (LT)	Baseline to 60 minutes after intervention	Change in Lens thickness (LT)
Pupillary diameter (PD)	Baseline to 60 minutes after intervention	Change in Pupillary diameter (PD)

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026