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Preemptive Analgesia of Gabapentoids in Orthopedic Surgery

Preemptive Analgesia of Gabapentoids After Major Orthopedic Surgery: Systematic Review and Meta Analysis

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04775992
Enrollment
1000
Registered
2021-03-01
Start date
2021-03-01
Completion date
2021-12-01
Last updated
2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Postoperative Pain

Keywords

acute postoperative pain, Preemptive analgesia, Orthopedic surgery, Preoperative gabapentoids

Brief summary

To address the preemptive analgesic effect of preoperative gabapentoids versus no gabapentoids in orthopedic surgery

Detailed description

Computer search for all studies used preoperative gabapentoids versus no gabapentoids in orthopedic surgery during the last 10 years (from 2011 - 2020)

Interventions

OTHERgabapentoids

Preemptive analgesia

Sponsors

King Saud University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* RCT, during last 10 years, involving orthopedic surgery

Exclusion criteria

* non randomized trials, unavailable study data

Design outcomes

Primary

MeasureTime frameDescription
Postoperative pain score on restevery hour for the first 24 hoursPain score by VAS on rest
Postoperative pain during movementevery hour for the first 24 hoursPain score by VAS during movements

Secondary

MeasureTime frameDescription
Worst pain scoreduring the first 24 hoursHighest pain score
Least pain scoreduring the first 24 hoursLowest pain score
Time spend in severe painduring the first 24 hourshow many hours the patients complaint of severe pain
Patient's satisfactionduring the first 24 hoursSatisfaction by the quality of analgesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026