Use of Perforated Barrier Membranes and IPRF Nano- Micro Sticky Bone

The Use of Perforated Barrier Membranes and IPRF Nano- Micro Sticky Bone in Horizontal Alveolar Ridge Augmentation - Controlled Clinical and Histomorphometric Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04775940

Enrollment

Registered

2021-03-01

Start date

2018-03-01

Completion date

2019-12-01

Last updated

2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Augmentation

Brief summary

Comparing amount of horizontal bone gain 4 months after alveolar ridge augmentation using IPRF Nano- micro Sticky Bone with perforated collagen membrane versus occlusive barrier membrane by : 1. clinical and Radiographic analysis . 2. Histomorphometric analysis .

Interventions

PROCEDUREPerforated collagen membrane

Horizontal Bone Augmentation using Perforated Collagen Membrane

PROCEDUREOcclusive collagen membrane

Occlusive collagen membrane

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

1. Healthy adult patients. 2. Both sex, males and females. 3-Age from 20 - 40 years old. 4-All patients will be free from any systemic diseases as evidenced by Burkett's oral medicine health history questionnaire. 5-Remaining alveolar bone ≥ 8mm vertically and ≤ 4 mm horizontally. 6-Gingival biotype 1-2mm thickness.

Exclusion criteria

1. Smokers. 2. Pregnant and breast feeding females. 3. Mentally retarded Patients. 4. Presence of hematologic disease. 5. Previous radiation, chemotherapy, or immunosuppressive treatments. 6. Diabetes mellitus, metabolic bone disease, ongoing treatment with bisphosphonates drugs, or pregnancy. 7. Anticoagulant drugs, Endocarditis risk factors, renal and hepatic failure

Design outcomes

Primary

Measure	Time frame	Description
Horizontal alveolar bone width in mm	6 months	Measured By Bone caliber and Cone Beam Computed Tomography (CBCT)

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026