MPV and NLR as Predictors of SBP Diagnosis

Mean Platelet Volume (MPV) and Neutrophil to Lymphocyte Ratio (NLR) as Predictors of Spontaneous Bacterial Peritonitis in Cirrhotic Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04775420

Enrollment

332

Registered

2021-03-01

Start date

2020-04-01

Completion date

2022-04-30

Last updated

2023-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spontaneous Bacterial Peritonitis

Keywords

Spontaneous bacterial peritonitis, Mean platelet volume, Neutrophil to lymphocyte ratio

Brief summary

The aim of the study is to investigate the clinical utility of mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) as diagnostic markers for spontaneous bacterial peritonitis (SBP).

Interventions

DIAGNOSTIC_TESTMeasurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR)

MPV and NLR are easily accessible and inexpensive tests

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Decompensated liver cirrhosis ascetic patients.

Exclusion criteria

* Immunocompromised patients. * Patients who had received antibiotics before hospital admission. * Patients on anticoagulant medications, NSAIDs, or oral contraceptive drugs. * Patients with heart failure, diabetes mellitus, hypertension, hyperlipidemia, peripheral vascular disease, hematological disorders, and neoplastic disorders and patients with clinically overt hypothyroidism or hyperthyroidism or with clinically and laboratory-evident autoimmune diseases.

Design outcomes

Primary

Measure	Time frame	Description
The utility of MPV as non-invasive predictor of SBP	1 year	It will be measured from CBC
The utility of NLR as non-invasive predictor of SBP	1 year	It will be measured from CBC

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026