Hip Arthritis, Juvenile Idiopathic Arthritis
Conditions
Brief summary
Patients having juvenile idiopathic arthritis (according to ILAR criteria) with hip arthritis were divided into 3 groups. Group 1 received hip denervation and group 2 controlled and received a subcutaneous injection of saline, and group 3 received intra-articular triamcinolone. Outcome measures included pain, tenderness, range of motion, SOLAR, HARISS score. These outcomes were measured at baseline, 2 weeks, and 16 weeks
Detailed description
The aim of the study is to test the effect of denervation of the active hip in JIA and compare it with a placebo without changing systemic treatment during the study. Outcome measures included pain, range of motion, SOLAR score, and Harris functional score.
Interventions
DRUGLidocaine
denervation of the obturator and femoral genicular branches by Lidocaine 2 %
DRUGPlacebo
an equivalent amount of saline will be injected subcutaneously in 2 points similar to the active group
DRUGSteroid
Intra-articular injection of 80mg of triamcinolone
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Masking description
double-blinded
Eligibility
Sex/Gender
ALL
Age
2 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* patients with JIA with unilateral hip arthritis
Exclusion criteria
* hip involvement due to other causes including * septic arthritis * other connective tissue diseases * Avascular necrosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| semiquantitative tenderness score | Baseline, 2 weeks and 16 weeks | 0 means no tenderness and 3 means maximum tenderness |
| Change in SOLAR score | Baseline, 2 weeks and 16 weeks | GSUS. 0 means the least synovitis and the maximum, PDUS, o means no PD and 3 the maximum |
| Change in visual analogue scale | Baseline, 2 weeks and 16 weeks | a scale from 0-100 will be used 0 means no pain 100 means the maximum pain |
| Change in range of motion | Baseline, 2 weeks and 16 weeks | flexion, internal rotation, external rotation range will be calculated |
| Change in Harris functional score | Baseline, 2 weeks and 16 weeks | 100 means best results and 0 means worst results |
Countries
Egypt
Outcome results
None listed