Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Intractable Epilepsy

Microendoscopic Transventricular Deep Brain Stimulation of the Anterior Nucleus of the Thalamus as a Safe and Efficient Treatment in Intractable Epilepsy

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04771065

Enrollment

Registered

2021-02-25

Start date

2021-01-01

Completion date

2021-12-29

Last updated

2021-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractory Epilepsy

Keywords

epilepsy, deep brain stimulation, thalamus, endoscopy, stereotaxy

Brief summary

Deep Brain Stimulation (DBS) of the anterior nucleus of the thalamus (ANT) has been proposed in patients with severe intractable epilepsy. When used, the transventricular approach increases the risk of bleeding due the anatomy around the entry point in the thalamus. To avoid such a complication, the investigators used a transventricular microendoscopic technique.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* adult patients * treated between 2010 and 2019 for refractory epilepsy by DBS of the anterior nucleus os the thalamus using microendoscopy * minimum follow-up of 1-year * refractory epilepsy defined as failure of at least 3 antiepileptic drugs

Exclusion criteria

\- age \< 18 years

Design outcomes

Primary

Measure	Time frame	Description
Absence of hemorraghic complication	1 day	Absence of hemorraghic complication on post operative MRI

Secondary

Measure	Time frame	Description
responder rate	1 year	50%-responder rate (on seizures)

Countries

France

Contacts

Primary ContactGaëtan Poulen, MD

g-poulen@chu-montpellier.fr467337262

Outcome results