Protect and Improve Cluster of Differentiation 4 (CD4) Cells and B Cells Lymphocytes

Extracts of Plants Eclipta Prostrata, Dioscorea Cirrhosa, Phyllanthus Urinaria, Adenosma Glutinosum, Impatiens Balsamina and Ascorbic Acid Use for in Protecting and Increasing CD4+ T Lymphocytes; B Lymphocytes Level in HIV/AIDS Patients.

Status

Withdrawn

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04770701

Enrollment

Registered

2021-02-25

Start date

2020-09-20

Completion date

2026-06-06

Last updated

2026-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AIDS, HIV-1-infection

Brief summary

This is a plant-based medication used to increase the amount, protect, and reduce HIV's impact on T and B lymphocytes.

Detailed description

Dioscorea cirrhosa, impatiens balsamina, eclipta prostrata, phyllanthus urinaria, adenosma glutinosum, and ascorbic acid are used to elevate T and B lymphocytes level, protect their cells membrane, decrease the damage of HIV on CD4+ T. In detail, Diosgenin presented in dioscorea cirrhosa is a precursor of cortisol. Dioscorea cirrhosa when combined with ascorbic acid helps to balance cortisol levels which reduces cell inflammation. Flavonoids of dioscorea cirrhosa also help to increase CD4+ T levels. impatiens balsamina can be used as an antitoxin alternative against bacteria or viruses. Flavonoids in impatiens balsamina, such as kaempferol, quercetin, rutin, astragalin, have the ability to reduce the virus's impact on T lymphocyte, protect their cell membrane, produce antihistamine, protect the cell from inflammation. Targeted flavonoids in eclipta prostrata, phyllanthus urinaria, adenosma glutinosum are used to cell repair, protect and increase CD4+ T production. Ascorbic acid in combination with herbal extracts creates a favorable environment for body metabolism, improves the medication's effectiveness.

Interventions

DRUGAhah Drug

\- Composition Ahah containing concentrated extracts of plants: Eclipta prostrata, dioscorea cirrhosa, phyllanthus urinaria, adenosma glutinosum, impatiens balsamina and ascorbic acid. -Take 1tablet x 2 times / 24 hours. Maintained for 9 months.

DEVICEAhah Placebo

\- Composition Ahah (not containing concentrated extracts of plants): Eclipta prostrata, dioscorea cirrhosa, phyllanthus urinaria, adenosma glutinosum, impatiens balsamina and ascorbic acid. -Take 1tablet x 2 times / 24 hours. Maintained for 9 months.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Masking description

The group of HIV / AIDS uses drugs under study. The group of HIV / AIDS uses a placebo.

Intervention model description

60 people were recruited HIV / AIDS positive between the ages of 20 and 60 and divided into 2 groups according to a random distribution.

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Participants have a decline in CD4 + T-lymphocytes is the hallmark of HIV-1 infection. Characterized by rapid loss of resistance: AIDS * Dermatitis, mouth ulcers, skin rash, itching, weight loss * HCV (+), HBV (+), Tuberculosis (+)

Exclusion criteria

* Cancer under all form

Design outcomes

Primary

Measure	Time frame	Description
The CD4 cell count measurement	- 9 months	HIV is a fatal infection, characterized by the targeting and destruction of CD4 T lymphocytes in the peripheral blood.

Countries

Vietnam

Contacts

PRINCIPAL_INVESTIGATORTran Minh Duc, Dr.

Trieu, Nguyen Thi, M.D.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 5, 2026