A Clinical Trial Evaluating the Efficacy of a Skin Cream in Improving Facial Appearance and Skin Elasticity

A Clinical Trial Evaluating the Efficacy of a Skin Cream Targeting Dermal Fat in Improving the Skin Elasticity of Healthy Volunteers

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04769193

Enrollment

Registered

2021-02-24

Start date

2021-01-27

Completion date

2022-04-15

Last updated

2026-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrophy, Hemifacial, Elastosis, Photoaging

Keywords

Sagging, Depletion, Atrophy, Photoaging

Brief summary

A Clinical Trial Evaluating Efficacy of a Skin Cream Targeting Dermal Fat in Improving the Skin Elasticity of Healthy Volunteers.

Detailed description

This is a single-arm study with subjects serving as their own controls. The study evaluates a face cream comprised of natural agents with adipogenic and lipolytic activities. The combination of adipogenic and lipolytic impulses is theorized to be more effective in promoting regeneration and healthy cell size in the dermal white adipose tissue than other approaches (e.g., adipogenic + lipogenic or anti-adipogenic + lipolytic). The health of the dermal white adipose tissue is reflected by the strength and elasticity of the skin and the distribution of volume in the face.

Interventions

OTHERAdipeau face cream

Adipeau face cream contains the natural actives Carthamus Tinctorius (Safflower) Seed Oil and Kaempferia Parviflora Rhizome Extract (Black Ginger).

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Masking description

The evaluation of skin volume will be masked as the assessors will not known which scans are from what time period.

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

Exclusion criteria

* Plans to undergo facial skin resurfacing (e.g. laser, chemical peel, microneedling) during the study period * Plans to undergo injectable filler treatment.

Design outcomes

Primary

Measure	Time frame	Description
Change in Skin Elasticity	Six months and 12 months..	Elasticity measured by DermaLab Skin Elasticity Meter.
Change in Skin Volume	Six months and 12 Months.	Increases and decreases measured by Cherry Imaging 3D Scanning System.

Secondary

Measure	Time frame	Description
FaceQ skin satisfaction surveys	Two, Six and 12 Months.	Satisfaction With Skin, Appraisal of Lower Eyelids, Satisfaction with Cheeks, Adverse Effects

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORJacob Tower, MD

Romo Plastic Surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 12, 2026