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Acute Kidney Injury as a Risk Factor for Myocardial Injury and Ventricular Dysfunction

Assessment of Acute Kidney Injury as a Risk Factor for Myocardial Injury and Ventricular Systolic Dysfunction After Non-Cardiac Surgery in Critical Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04768751
Enrollment
520
Registered
2021-02-24
Start date
2019-03-05
Completion date
2020-08-30
Last updated
2021-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury, Myocardium; Injury, Ventricular Dysfunction

Brief summary

Acute kidney injury (AKI) is classically described as an abrupt or rapidly reversible reduction in the excretion of nitrogenous waste products, including urea, nitrogen and creatinine. Acute kidney injury definition emphasizes on the filtration function of the kidney, a measure that is unique and easily and routinely measured . Acute kidney injury is associated with significantly increased resource utilization and health care costs. Major adverse cardiac events (MACE) after non cardiac surgery are a leading cause of morbidity and mortality. The reported incidence of postoperative myocardial infarction (POMI) among patients undergoing non cardiac surgery is between 3% and 6%.

Interventions

DIAGNOSTIC_TESTkidney assessment

Urea, BUN, and Creatinine BLOOD LEVELS

Sponsors

South Egypt Cancer Institute
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Patients with normal kidney functions and free normal heart functions, were enrolled to this study

Exclusion criteria

* patients with chronic kidney disease, cardiac disease, who with minor operations, or emergency, were excluded from the study.

Design outcomes

Primary

MeasureTime frameDescription
development myocardial injurythrough study completion, an average of 15 daysNew echocardiographic findings suggestive of ischemia (new regional wall motion abnormalities) or cardiac troponin T \>.0.32 ng/ml

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026