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Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis.

Efficacy of Cuminum Cyminum Herbal Preparation in Inhibition of Plaque and Gingivitis

Status
Completed
Phases
Phase 2Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04767269
Enrollment
30
Registered
2021-02-23
Start date
2019-01-01
Completion date
2021-01-31
Last updated
2021-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Gingivitis

Keywords

Mouthwash, chlorhexidine, stain

Brief summary

Present work was to investigate the possible efficacy of 0.2% cuminum cyminum herbal preparation as an antiplaque and antigingivitis agent when compared with chlorhexidine.

Detailed description

To evaluate and compare the efficacy of 0.2% cuminum cyminum herbal preparation against 0.2% chlorhexidine by various clinical parameters i.e. plaque index, gingival index and sulcus bleeding index.

Interventions

DRUGCuminum Cyminum

Cuminum Cyminum mouthwash in chronic gingivitis patients

herbal mouthwash in chronic gingivitis patients

Sponsors

Maharishi Markendeswar University (Deemed to be University)
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Intervention model description

1. Group phase A 2. Group phase B 3. Group phase C

Eligibility

Sex/Gender
ALL
Age
23 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* volunteers with minimum 20 natural teeth without restoration. * cooperative * motivated and committed to participate in the trial period.

Exclusion criteria

* Antibiotic or anti-inflammatory therapy in previous month. * Any known allergy/ hypersensitivity to any product used in trial.

Design outcomes

Primary

MeasureTime frameDescription
PLAQUE INDEXchanges from baseline to 8 daysPLAQUE INDEX: Turesky-Gilmore-Glickman Modification of Quigley Hein 1962
Gingival Indexchanges from baseline to 8 daysGingival Index: Loe H ans Silness 1963
Bleeding on probingchanges from baseline to 8 daysBleeding on probing: Muhlemann HR and Son 1971

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026