Ischemic Cerebrovascular Accident
Conditions
Brief summary
The objective of the NEUTROSURGERY study is to describe the local and locoregional immuno-inflammatory activity in patients suffering from malignant sylvian ischaemic cerebral accident and treated with decompressive hemicraniectomy compared to a control population of patients to be operated on in neurosurgery for another neurosurgical pathology.
Interventions
Decompressive hemicraniectomy in the context of a malignat sylvian ischaemic cerebral accident
neurosurgical operation on which cranial, meningeal, vascular (branch of the middle meningeal artery) or cerebral bone tissue is not preserved during the surgical approach.
Sponsors
Study design
Eligibility
Inclusion criteria
Patients: * Collegial indication given by a neurologist, a neuroreanimator and a neurosurgeon for HD in the context of a malignant sylvian AIC. Inclusion Criteria Control: \- For neurosurgical operations in which cranial, meningeal, vascular (branch of the middle meningeal artery) or cerebral bone tissue is not preserved during the surgical approach. Non-inclusion Criteria Patients: * HD carried out in a context of acute cerebral haemorrhage * Pre-existing neurological disability: modified Rankin score \> 2 * Patient benefiting from a legal protection measure Non-inclusion Criteria Controls: * Patient to be operated on for an acute vascular condition: meningeal haemorrhage, subdural or extradural haemorrhage, intra parenchymal haemorrhage. * Patient operated on for an osteomeningeal pathology present at the approach site. * Patient operated on for an infectious cranial or neuro-meningeal pathology. * Patient to be operated on as a result of an intracranial traumatic condition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| neutrophil polynuclear cells levels | Day 0 |