Study of Metformin Overdose

Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04762966

Acronym

METINFO

Enrollment

Registered

2021-02-21

Start date

2021-03-01

Completion date

2021-09-01

Last updated

2021-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metformin Associated Lactic Acidosis

Keywords

Metformin, Lactic Acidosis, Causality assessment

Brief summary

The objective of the METINFO study is an observational single-center retrospective and descriptive study. The main objective is to estimate the real mortality rate associated to a Metformin overdose. Second objectives are to estimate the real hospitalization rate related to metformin overdose and to identify the risk factors of a metformin overdose and especially the potential correlation between metformin blood concentration and overdose severity.

Interventions

DRUGMetformin

Level of Metformin blood concentration

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patients benifiting of a metformin blood concentration determination in the period ranging from the 1st of July 2019 and the 1st of July 2021.

Exclusion criteria

None.

Design outcomes

Primary

Measure	Time frame
Estimation of Mortality Rate	2 years

Secondary

Measure	Time frame
Estimation of Hospitalization Rate	2 years
Identification of Risk Factors	2 years

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026